For professionals in the chemical and pharmaceutical industries, a solid understanding of available intermediates is key to driving innovation and ensuring efficient production. Imidazole-2-carboxaldehyde (CAS 10111-08-7) is one such compound, offering a unique combination of structural features and reactivity that makes it highly valuable. This article delves into its properties, diverse applications, and provides guidance for buyers on how to source it effectively.

Imidazole-2-carboxaldehyde, commonly known as 2-formylimidazole, is typically supplied as a white powder. Its chemical structure, C4H4N2O, with a molecular weight of 96.09, makes it a compact yet functional molecule. A notable physical characteristic is its relatively high melting point of approximately 209°C (with decomposition), which indicates good thermal stability. For optimal preservation of its quality, storage in a cool (2-8°C) and dry environment is recommended, ensuring its integrity for future use. The compound’s purity is generally high, often specified as 97% minimum by HPLC, which is critical for its demanding applications.

The versatility of Imidazole-2-carboxaldehyde is evident in its wide range of applications. It serves as a crucial intermediate in the pharmaceutical industry for the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates. Its imidazole core is a common motif in many biologically active molecules, making it a preferred building block for medicinal chemists developing new therapeutics, including those for infectious diseases or metabolic disorders. Beyond pharmaceuticals, it finds significant use in biochemical research as a tool for synthesizing enzyme inhibitors and probes to study biological pathways.

Furthermore, Imidazole-2-carboxaldehyde plays a role in materials science, particularly in coordination chemistry where it is used to create ligands for metal complexes. These complexes can function as catalysts, enhancing the efficiency of chemical reactions in various industrial processes, or form the basis for novel materials with unique electronic or structural properties. Its utility also extends to the food and fragrance industries, where it can contribute to specific aroma profiles.

For buyers seeking to purchase Imidazole-2-carboxaldehyde, identifying reliable suppliers is paramount. Many manufacturers in China offer this chemical at competitive prices, making them a primary source for global procurement. When selecting a supplier, it is important to request detailed product specifications, safety data sheets (SDS), and certificates of analysis (COA) to verify quality and ensure compliance. Always consider obtaining a sample to validate the product’s suitability for your specific needs before committing to a larger purchase order.

In summary, Imidazole-2-carboxaldehyde is a foundational intermediate in modern chemistry, offering significant utility in pharmaceuticals, biochemical research, and materials science. By understanding its properties and sourcing it from reputable manufacturers, researchers and procurement specialists can effectively utilize this compound to drive innovation and achieve their project goals.