Indole-3-carboxaldehyde, identified by its CAS number 487-89-8, is a compound of significant interest in organic chemistry and related industries. This article provides an in-depth look at its key properties, common synthesis routes, and the wide spectrum of its applications. As a leading manufacturer and supplier, we aim to offer this vital intermediate with the highest standards of quality and reliability.

Chemical Properties and Appearance: Indole-3-carboxaldehyde typically presents as a light yellow crystalline powder. Its molecular formula is C9H7NO, with a molecular weight of 145.16 g/mol. It exhibits a melting point in the range of 196-198°C, indicating its solid state at room temperature. The compound is known for its general aldehyde properties, allowing it to participate in a variety of chemical reactions. Its solubility characteristics often include being slightly soluble in cold water and readily soluble in organic solvents like ethanol.

Synthesis Methods: The synthesis of Indole-3-carboxaldehyde can be achieved through several established organic chemistry methods. Historically, formylation of indole using reagents such as phosphorus oxychloride and dimethylformamide (Vilsmeier-Haack reaction) is a common and effective route. Other methods include the Reimer-Tiemann reaction and various oxidation or condensation reactions starting from indole derivatives. As a dedicated manufacturer, we employ optimized synthesis protocols to ensure high yields and purity.

Applications: The versatility of Indole-3-carboxaldehyde lies in its broad range of applications. It is a crucial intermediate in the synthesis of bioactive indole alkaloids, which are key components in many pharmaceuticals. These include compounds used as antitumor agents, antidepressants, and antimicrobial drugs. Beyond pharmaceuticals, it finds use in the agrochemical industry for synthesizing plant growth regulators and pesticides. Its aldehyde functionality also makes it valuable in the creation of dyes, fluorescent probes, and other specialty organic chemicals. Procurement of high-purity Indole-3-carboxaldehyde from a reliable supplier in China is essential for these applications.

For those seeking to buy Indole-3-carboxaldehyde, understanding these facets ensures informed decision-making. We are committed to being a premier supplier, offering consistent quality and competitive pricing for this indispensable chemical intermediate.