In the realm of specialty chemicals and pharmaceutical intermediates, understanding the properties and applications of key compounds is vital for professionals in research, development, and procurement. Indole-5-Carbonitrile, more commonly known as 5-Cyanoindole (CAS 15861-24-2), is one such compound that plays a significant role in various synthetic processes, particularly within the pharmaceutical sector. This article aims to provide a comprehensive overview of this chemical, its applications, and how to effectively source it from reliable manufacturers.

What is Indole-5-Carbonitrile?

Indole-5-Carbonitrile is an organic compound characterized by its off-white crystalline powder appearance. Its molecular formula is C9H6N2, and its chemical structure combines the classic indole ring system with a nitrile functional group at the 5th position. This combination makes it a versatile intermediate in organic synthesis. The typical purity specified by manufacturers, such as NINGBO INNO PHARMCHEM CO.,LTD., is often 98% or 99% minimum assay, ensuring its suitability for demanding applications like pharmaceutical intermediate synthesis.

Key Applications and Industry Relevance

The primary application of Indole-5-Carbonitrile is as a crucial building block in the synthesis of Active Pharmaceutical Ingredients (APIs). Its indole core is a common structural motif in many drugs targeting a wide range of therapeutic areas, including oncology, neurology, and infectious diseases. The nitrile group provides a reactive site for further chemical modifications, enabling the construction of complex molecular architectures necessary for drug efficacy.

Beyond pharmaceuticals, its chemical structure may also lend itself to applications in:

  • Agrochemicals: Certain pesticides and herbicides utilize indole derivatives.
  • Materials Science: As a fine chemical intermediate, it might find use in the development of specialized materials.
  • Research and Development: It serves as a valuable reagent for academic and industrial research laboratories exploring new chemical reactions and compounds.

For professionals seeking to buy Indole-5-Carbonitrile, understanding its specific role in their intended application is key to selecting the right grade and supplier.

Sourcing Strategies for Indole-5-Carbonitrile

When sourcing chemical intermediates, it is imperative to work with reliable suppliers who can guarantee quality and consistency. Key considerations include:

  • Manufacturer Reputation: Partnering with experienced manufacturers, especially those recognized as a leading 5-Cyanoindole manufacturer, is crucial.
  • Quality Documentation: Always request a Certificate of Analysis (CoA) detailing the product's specifications, including assay, purity, and any identified impurities. Safety Data Sheets (SDS) are also essential.
  • Competitive Pricing: Obtain quotes from multiple suppliers to ensure you are getting a fair market price for the quality required. Investigating CAS 15861-24-2 price from various sources can reveal cost-saving opportunities.
  • Supply Chain Reliability: Ensure the supplier has a robust production capacity and logistics network to meet your demand consistently.

Working with a specialized 5-Cyanoindole supplier in regions like China can offer advantages in terms of both cost and scale. Companies that adhere to international quality standards provide the assurance needed for pharmaceutical and high-value chemical applications.

In summary, Indole-5-Carbonitrile is a vital chemical intermediate with broad applications, particularly in pharmaceutical synthesis. By focusing on sourcing from reputable manufacturers and understanding the critical quality parameters, professionals can effectively meet their chemical procurement needs.