Understanding [Lys3]-Bombesin: Properties and Supplier Considerations
[Lys3]-Bombesin is a synthetic peptide that has garnered significant attention in the fields of oncology and medical imaging due to its specific affinity for the Gastrin-Releasing Peptide Receptor (GRPR). As a crucial intermediate for developing targeted therapies and diagnostic agents, understanding its properties and how to source it reliably is vital for researchers and procurement professionals.
Chemically, [Lys3]-Bombesin is a tetradecapeptide, meaning it consists of fourteen amino acids. Its sequence is Pyr-Gln-Lys-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2, with a molecular weight of approximately 1592 Da. This structure allows it to bind with high affinity to GRPRs, which are overexpressed in various types of cancer, most notably prostate cancer. This specific interaction is the basis for its utility in PET imaging, where radiolabeled versions of the peptide can be used to visualize GRPR-positive tumors.
When considering purchasing [Lys3]-Bombesin, several factors are important. First, as previously mentioned, purity is critical. Suppliers should provide detailed analytical data, such as HPLC chromatograms, confirming the peptide's purity and identity. Second, consistency in quality from batch to batch is essential for reproducible research and clinical applications. A reputable manufacturer will have robust quality management systems in place to ensure this consistency.
Third, the ability to scale production is a key consideration for those planning to move from lab-scale research to clinical trials or commercialization. Partnering with a manufacturer that can scale up production while maintaining quality and competitive pricing is advantageous. As a manufacturer with extensive experience in peptide synthesis, we offer [Lys3]-Bombesin that meets these demanding requirements. We are committed to being a reliable supplier for researchers and companies working on GRPR-targeted diagnostics and therapeutics. When you need to buy [Lys3]-Bombesin, consider our expertise and dedication to quality to ensure your projects are built on a solid foundation.
Perspectives & Insights
Core Pioneer 24
“[Lys3]-Bombesin is a synthetic peptide that has garnered significant attention in the fields of oncology and medical imaging due to its specific affinity for the Gastrin-Releasing Peptide Receptor (GRPR).”
Silicon Explorer X
“As a crucial intermediate for developing targeted therapies and diagnostic agents, understanding its properties and how to source it reliably is vital for researchers and procurement professionals.”
Quantum Catalyst AI
“Chemically, [Lys3]-Bombesin is a tetradecapeptide, meaning it consists of fourteen amino acids.”