For pharmaceutical and food manufacturers relying on Microcrystalline Cellulose (MCC) for their formulations, understanding the nuances of different MCC grades is essential for optimizing product performance and manufacturing efficiency. As a premier supplier of MCC, we recognize that selecting the correct grade can significantly impact tabletability, flow characteristics, and the overall quality of your finished product. This guide aims to demystify the common MCC grades and highlight their specific applications, empowering you to make informed purchasing decisions.

Microcrystalline Cellulose is not a one-size-fits-all excipient. Its manufacturing process, involving acid hydrolysis of cellulose, yields different grades primarily distinguished by their particle size distribution, bulk density, and moisture content. These variations directly influence how MCC behaves in formulations, particularly in direct compression and granulation processes.

The Spectrum of MCC Grades:

  • MCC PH 101: The Finer Option
    Characterized by its fine particle size, MCC PH 101 is highly favored for wet granulation. Its smaller particle size contributes to excellent compressibility and good direct compression properties. This grade is often chosen when a very smooth tablet surface or specific disintegration profiles are desired. It’s a strong binder and can enhance the flow of fine powders when used in formulations.
  • MCC PH 102: The All-Rounder
    MCC PH 102 is arguably the most widely utilized grade due to its balanced properties. It offers an average particle size and exceptional compressibility, making it ideal for direct compression tableting. PH 102 provides a good combination of binding strength, disintegration, and flow, making it a workhorse excipient suitable for a broad range of applications. Many manufacturers prefer PH 102 for its consistent performance and high dilution capacity.
  • MCC PH 200: The Flow Improver
    For formulations where powder flow is a critical challenge, MCC PH 200 is an excellent choice. Its larger particle size compared to PH 101 and PH 102 significantly improves flowability. This grade is particularly beneficial for high-speed tableting operations or when dealing with APIs that have poor flow characteristics, helping to ensure uniform die filling and tablet weight.
  • Higher Bulk Density Grades (e.g., PH 301, PH 302): Tailored Properties
    Grades like PH 301 and PH 302 are known for their higher bulk densities. These properties can influence tablet compaction and provide specific benefits in certain formulations, such as improved tablet hardness or altered disintegration profiles. The selection of these grades typically depends on specific formulation requirements and extensive testing.

Why Buy MCC in Bulk from Us?
As a leading manufacturer and supplier based in China, we are committed to providing consistent quality and reliability for bulk purchases. Our MCC grades are produced under strict quality control measures, ensuring adherence to pharmacopeial standards where applicable. We offer competitive pricing, ensuring cost-effectiveness for your large-scale manufacturing needs. Furthermore, our robust supply chain guarantees timely delivery, minimizing disruptions to your production schedule. Whether your focus is on pharmaceuticals, food products, or nutraceuticals, we have the right MCC grade to meet your formulation's demands. Contact us to discuss your specific requirements and discover how our premium MCC can enhance your products.