Understanding Methyl 3,4-Difluorobenzoate for ALK5 Inhibitor Synthesis
Methyl 3,4-Difluorobenzoate, identified by CAS number 369-25-5, is a chemical compound of significant interest in the pharmaceutical industry. Its unique structure, featuring two fluorine atoms on a benzoate ester core, makes it a valuable building block for complex organic synthesis, particularly in the development of novel therapeutic agents. As a reputable manufacturer based in China, we specialize in providing high-quality chemical intermediates like Methyl 3,4-Difluorobenzoate to researchers and companies worldwide.
The primary application of Methyl 3,4-Difluorobenzoate lies in its role as a key intermediate for the preparation of disubstituted 1,5-Naphthyridines. These compounds are well-known for their potent ALK5 inhibitory activity. ALK5, or activin receptor-like kinase 5, is a serine/threonine kinase that plays a crucial role in various physiological processes, including cellular proliferation, differentiation, and extracellular matrix remodeling. Dysregulation of ALK5 signaling has been implicated in numerous diseases, such as fibrosis, cancer, and cardiovascular disorders. Therefore, ALK5 inhibitors are actively being researched as potential treatments for these conditions.
For scientists and procurement managers looking to buy Methyl 3,4-Difluorobenzoate, understanding its specifications is paramount. Typically supplied as an off-white powder with a purity of 97% or higher, this compound offers consistent quality for laboratory and industrial applications. Its melting point ranges from 23-27°C, indicating its solid state at room temperature. The availability of a free sample from our company allows potential customers to evaluate its suitability for their specific research and development projects before committing to bulk purchases.
Sourcing pharmaceutical intermediates requires a reliable supplier that can guarantee both quality and consistency. Our commitment as a Chinese chemical manufacturer is to provide a stable supply chain for Methyl 3,4-Difluorobenzoate, ensuring that your production timelines are met without interruption. We understand the competitive landscape and strive to offer not only high-grade products but also attractive prices for bulk orders. This makes us an ideal partner for companies seeking cost-effective solutions without compromising on quality.
In conclusion, Methyl 3,4-Difluorobenzoate (CAS:369-25-5) is an indispensable intermediate for those involved in the synthesis of ALK5 inhibitors and other advanced pharmaceutical compounds. We invite you to inquire about our products and discover how our reliable supply, high purity, and competitive pricing can support your ongoing research and manufacturing endeavors. Contact us today to discuss your requirements and obtain a quote or a free sample.
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Future Analyst X
“In conclusion, Methyl 3,4-Difluorobenzoate (CAS:369-25-5) is an indispensable intermediate for those involved in the synthesis of ALK5 inhibitors and other advanced pharmaceutical compounds.”