Methyl Acetoacetate (MAA), identified by CAS number 105-45-3, is a colorless liquid with a characteristic fruity odor, making it a compound of considerable interest across multiple industrial sectors. Its chemical structure, a beta-keto ester, endows it with significant reactivity, positioning it as a vital intermediate and building block in organic synthesis. For chemists, formulators, and procurement specialists, understanding MAA’s properties and applications is key to leveraging its potential. As a dedicated Methyl Acetoacetate manufacturer, we provide essential insights for sourcing this versatile chemical.

Physically, Methyl Acetoacetate is a clear, colorless liquid with a boiling point around 169-171 °C and a melting point of approximately -80 °C. Its density is slightly higher than water, around 1.076 g/cm³. These properties make it suitable for various liquid-phase reactions and formulations. Chemically, MAA is known for its active methylene group, which readily undergoes reactions like alkylation, acylation, and condensation, including the widely used Knoevenagel condensation and Biginelli reactions. This reactivity is fundamental to its utility as an intermediate.

The applications of Methyl Acetoacetate are extensive and diverse. In the pharmaceutical industry, it is a crucial intermediate for synthesizing a wide range of drugs, including antibiotics, vitamins, and analgesics. For agrochemical production, MAA serves as a precursor for herbicides, pesticides, and fungicides, contributing to crop protection. Its pleasant odor also makes it valuable in the flavor and fragrance industry for perfumes, cosmetics, and food additives. Furthermore, it finds use in the production of polymers, resins, coatings, and as a specialized solvent.

When seeking to buy Methyl Acetoacetate, particularly in bulk, identifying a reliable Methyl Acetoacetate supplier is paramount. Key considerations include product purity (typically >99%), consistent batch quality, and competitive pricing. Engaging with a direct manufacturer in China can offer significant advantages in terms of cost and supply chain reliability. Always request detailed technical data, including CoAs and MSDS, to ensure the material meets your specific requirements for synthesis or formulation.

Whether your interest lies in pharmaceutical intermediates, agrochemical building blocks, or flavor and fragrance ingredients, Methyl Acetoacetate is a chemical that offers substantial value. By partnering with experienced manufacturers and understanding the critical parameters for quality and procurement, you can effectively source this essential compound to drive your innovations forward.