For researchers delving into the complexities of genetic mutations and cancer development, understanding the tools available is paramount. Among these, 1-Methyl-3-nitro-1-nitrosoguanidine, commonly known as MNNG (CAS 70-25-7), stands out as a powerful and widely utilized chemical mutagen. This article aims to provide an in-depth look at MNNG, its scientific significance, and how procurement professionals can secure this vital compound from reputable manufacturers and suppliers.

MNNG is a potent alkylating agent that functions by inducing DNA damage, specifically through methylation of guanine and thymine bases. This targeted damage can lead to transition mutations, making it an invaluable tool for scientists studying genetic instability and the mechanisms of carcinogenesis. Its ability to reliably induce mutations has led to its widespread use in creating experimental models for various cancers, most notably gastric carcinoma in animal studies. This controlled induction allows researchers to investigate disease progression, test therapeutic interventions, and explore preventative strategies.

When considering the purchase of MNNG, researchers and procurement managers must prioritize purity and reliability. As a specialized chemical, MNNG is best sourced from manufacturers with a proven track record in producing high-quality research chemicals. Suppliers offering detailed certificates of analysis (COA) and ensuring strict quality control measures are essential partners for any research endeavor. For those looking to buy 1-Methyl-3-nitro-1-nitrosoguanidine, seeking out suppliers who can provide competitive pricing, such as those found in China, can also be a strategic advantage, especially for bulk orders.

The practical applications of MNNG extend beyond simply inducing mutations. It plays a crucial role in:

  • Genetic Research: Studying DNA repair pathways, gene function, and the process of mutagenesis.
  • Cancer Model Development: Creating precise animal models for preclinical drug screening and efficacy testing.
  • Toxicology Studies: Investigating the mechanisms of chemical carcinogenicity and developing safety protocols.

When engaging with a 1-Methyl-3-nitro-1-nitrosoguanidine manufacturer, it's important to discuss your specific needs, including desired purity levels and quantities. The price of CAS 70-25-7 can vary based on these factors, as well as the supplier's location and reputation. Establishing a relationship with a dependable 1-Methyl-3-nitro-1-nitrosoguanidine supplier ensures a consistent supply chain, minimizing disruptions to your research schedule. Whether you are looking to order MNNG for routine laboratory use or for a large-scale research project, prioritizing a reliable source is key to achieving your scientific objectives.

In conclusion, 1-Methyl-3-nitro-1-nitrosoguanidine (MNNG) is a cornerstone chemical in the fields of genetics and cancer research. By understanding its properties and applications, and by strategically partnering with trusted manufacturers and suppliers, researchers can effectively leverage this powerful tool to advance scientific discovery. We are proud to be a leading manufacturer and supplier of MNNG, offering high-purity products at competitive prices to support your critical work.