For professionals in the chemical and pharmaceutical industries, a deep understanding of key intermediates is crucial for innovation and efficient production. N-Boc-4-(tosyloxymethyl)piperidine (CAS 166815-96-9) is one such compound, widely recognized for its utility in complex organic synthesis. This detailed look explores its chemical characteristics, applications, and why sourcing it from a reliable manufacturer is a strategic decision.

N-Boc-4-(tosyloxymethyl)piperidine is a white-yellow crystalline powder with a molecular formula of C18H27NO5S and a molecular weight of 369.48 g/mol. Its structure features a piperidine ring protected with a tert-butyloxycarbonyl (Boc) group and substituted with a tosyloxymethyl moiety. This combination makes it an excellent intermediate for reactions requiring controlled functionalization of the piperidine scaffold. The tosylate group serves as a good leaving group, facilitating nucleophilic substitution, while the Boc group can be selectively removed to expose the amine for further reactions. Understanding these features is vital when you intend to buy N-Boc-4-(tosyloxymethyl)piperidine.

The primary application for this intermediate is in the synthesis of pharmaceuticals, notably as a precursor for Vandetanib, a targeted therapy for certain types of cancer. Its structured reactivity also makes it valuable in medicinal chemistry research for creating novel drug candidates and exploring structure-activity relationships. When seeking to purchase N-Boc-4-(tosyloxymethyl)piperidine, professionals look for suppliers who guarantee high purity (≥98.0%) to ensure the efficacy and safety of the final pharmaceutical products. A leading N-Boc-4-(tosyloxymethyl)piperidine supplier, especially one based in China, often provides a strong combination of quality and competitive CAS 166815-96-9 intermediate price.

For any laboratory or manufacturing facility, ensuring a consistent and dependable supply of this intermediate is key. Whether you are looking for small quantities for R&D or bulk amounts for production, partnering with a reputable pharmaceutical intermediate manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is advisable. They can offer not only the required quality but also a stable supply chain, ensuring your projects are not hindered by material shortages.

In summary, N-Boc-4-(tosyloxymethyl)piperidine is a critical fine chemical intermediate with significant applications in pharmaceutical synthesis. Its specific chemical properties, combined with the need for high purity and reliable sourcing, make it essential to work with experienced manufacturers and suppliers who understand the demands of the industry.