In the realm of pharmaceutical chemistry, certain molecules stand out due to their critical roles as intermediates or reference standards. N-Boc-Aliskiren, identified by its CAS number 173338-07-3, is one such compound, gaining recognition among R&D scientists and procurement specialists in the pharmaceutical sector.

Chemical Identity and Properties of N-Boc-Aliskiren

N-Boc-Aliskiren is chemically known as tert-Butyl N-[(1S,2S,4S)-4-[[(3-amino-2,2-dimethyl-3-oxopropyl)amino]carbonyl]-2-hydroxy-1-[(2S)-2-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-3-methylbutyl]-5-methylhexyl]carbamate. Its molecular formula is C35H61N3O8, and it possesses a molecular weight of approximately 651.87 g/mol. Key physical properties often include a white powdery appearance and a melting point typically in the range of 138-142°C. Proper storage, usually under refrigeration at 2-8°C, is essential to maintain its stability and purity.

Applications in Pharmaceutical Research and Manufacturing

The primary significance of N-Boc-Aliskiren lies in its application as a pharmaceutical intermediate. It is an impurity and a key precursor in the synthesis of Aliskiren, a groundbreaking drug used for treating hypertension. Its presence as an impurity also makes it an important reference standard for analytical testing and quality assurance in Aliskiren production. Researchers often utilize it to understand synthesis pathways, develop analytical methods, and ensure the purity of the final Aliskiren hemifumarate product.

Navigating the Supply Chain: Purchasing N-Boc-Aliskiren

For professionals in the pharmaceutical industry, sourcing this intermediate requires careful consideration of suppliers. Key factors include not only the price of N-Boc-Aliskiren but also the supplier's reputation for quality, consistency, and regulatory compliance. Manufacturers and suppliers offer various packaging sizes, from grams for laboratory research to kilograms for pilot-scale production. When you buy N-Boc-Aliskiren, engaging with a reputable manufacturer in China or other global regions ensures that you are obtaining a product that meets stringent quality specifications and is supplied reliably.

Understanding the technical specifications, applications, and sourcing options for N-Boc-Aliskiren is crucial for successful R&D and manufacturing. Its role as both an intermediate and a reference standard highlights its indispensability in the pharmaceutical supply chain.