Understanding N-Lauroylsarcosine (CAS 97-78-9) for Enhanced Skin Penetration
The efficacy of topical and transdermal formulations hinges significantly on the ability of active pharmaceutical ingredients (APIs) and cosmetic actives to penetrate the skin's protective layers. The stratum corneum, the outermost layer of the epidermis, presents a formidable lipid-rich barrier that limits the passage of many beneficial compounds. Understanding the mechanisms of penetration enhancers, such as N-Lauroylsarcosine (CAS: 97-78-9), is crucial for developing advanced delivery systems.
N-Lauroylsarcosine functions as a non-ionic surfactant that is believed to enhance skin penetration through multiple pathways. Primarily, it interacts with the intercellular lipids of the stratum corneum, transiently disrupting their highly organized structure. This disruption increases the fluidity of the lipid matrix, creating more pathways for the diffusion of dissolved APIs. Studies suggest it may also influence the keratin structure, further aiding passage. Its molecular structure, with a hydrophobic lauroyl chain and a hydrophilic sarcosine head group, is key to its amphipathic nature and its interaction with skin lipids.
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For those looking to buy N-Lauroylsarcosine, understanding its mechanism of action empowers informed decisions. We encourage inquiries about our product's specifications and the competitive N-Lauroylsarcosine price we offer. Partnering with a reliable Chinese manufacturer like NINGBO INNO PHARMCHEM ensures you receive a consistent and high-purity product that can unlock new potentials in your formulation development. Let us help you achieve superior results through advanced chemical solutions.
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