Understanding N-Oleoylethanolamine: A Key Lipid Mediator for Research
N-Oleoylethanolamine (OEA), identified by CAS number 111-58-0, is a naturally occurring fatty acid amide that plays a significant role in various biological processes. As a lipid mediator, it has garnered considerable attention in the scientific community for its potent bioactivities, making it a sought-after compound for researchers in fields ranging from metabolic health to oncology. Understanding its properties and applications is crucial for any B2B procurement manager or research scientist looking to advance their studies.
One of the most well-documented functions of N-Oleoylethanolamine is its role as a selective agonist for the peroxisome proliferator-activated receptor alpha (PPARα). PPARα is a nuclear receptor that regulates the expression of genes involved in lipid metabolism, fatty acid oxidation, and inflammation. Consequently, OEA's activation of PPARα has been linked to potential therapeutic benefits in managing conditions such as obesity, diabetes, and dyslipidemia. Researchers often seek high-purity OEA to accurately investigate these mechanisms, making it a critical component for many preclinical studies. If you are looking to buy N-Oleoylethanolamine for your research into metabolic regulation, ensuring you source from a reliable supplier in China is paramount for both quality and cost-effectiveness.
Beyond its metabolic effects, N-Oleoylethanolamine is also recognized as an inhibitor of ceramidase, an enzyme crucial for the breakdown of ceramides. Ceramides are a class of sphingolipids involved in fundamental cellular processes, including apoptosis (programmed cell death) and cell proliferation. By inhibiting ceramidase, OEA can influence ceramide levels, thereby impacting these cellular pathways. This property makes OEA a valuable tool for researchers investigating cancer cell growth, neuroprotection, and the intricate balance of lipid signaling within cells. For those requiring a ceramidase inhibitor for research, sourcing pure OEA from a reputable manufacturer is key to obtaining reproducible results.
The chemical structure of N-Oleoylethanolamine, derived from oleic acid and ethanolamine, contributes to its lipophilic nature and its ability to interact with various cellular targets. Its stability and well-defined chemical properties make it an ideal candidate for inclusion in biochemical assays and drug discovery pipelines. When considering N-Oleoylethanolamine price, it's important to balance cost with the assurance of high purity and consistent supply, especially for large-scale research projects or early-stage pharmaceutical development. Companies specializing in fine chemicals and pharmaceutical intermediates, such as NINGBO INNO PHARMCHEM CO.,LTD., are well-positioned to meet these demands.
In summary, N-Oleoylethanolamine (CAS 111-58-0) is a compound of significant scientific interest, offering a dual role as a PPARα agonist and ceramidase inhibitor. Its applications span metabolic research, drug discovery, and cellular biology. For B2B professionals seeking to procure this essential chemical, partnering with a dependable N-Oleoylethanolamine supplier in China ensures access to high-quality material at competitive prices, facilitating advancements in scientific exploration and therapeutic development.
Perspectives & Insights
Alpha Spark Labs
“One of the most well-documented functions of N-Oleoylethanolamine is its role as a selective agonist for the peroxisome proliferator-activated receptor alpha (PPARα).”
Future Pioneer 88
“PPARα is a nuclear receptor that regulates the expression of genes involved in lipid metabolism, fatty acid oxidation, and inflammation.”
Core Explorer Pro
“Consequently, OEA's activation of PPARα has been linked to potential therapeutic benefits in managing conditions such as obesity, diabetes, and dyslipidemia.”