For professionals in the chemical and pharmaceutical industries, understanding the specifications and applications of key intermediates is fundamental to successful procurement and synthesis. N-Cbz-4-Piperidinecarboxylic Acid, identified by CAS number 10314-98-4, stands out as a crucial building block in organic chemistry, particularly within pharmaceutical research and development. This article aims to provide a clear overview of its characteristics, primary uses, and guidance on sourcing.

N-Cbz-4-Piperidinecarboxylic Acid, also referred to as 1-Carbobenzoxy-4-piperidinecarboxylic acid or N-Cbz-isonipecotic acid, is chemically defined by its molecular formula C14H17NO4 and a molecular weight of approximately 263.29 g/mol. Typically, it presents as a white to off-white crystalline powder, indicating a stable solid form suitable for storage and handling. A critical specification for users is its purity, with suppliers often guaranteeing levels of 97% or higher, assessed via techniques like Gas Chromatography (GC).

The utility of N-Cbz-4-Piperidinecarboxylic Acid stems from its structure, which incorporates a protected amine function (via the Cbz group) and a reactive carboxylic acid moiety on a piperidine ring. This makes it a highly versatile intermediate for constructing more complex molecular architectures. Its applications are widespread, most notably in:

  • Pharmaceutical Synthesis: It serves as a core component in the synthesis of various drug candidates and APIs, where the piperidine scaffold is a common feature.
  • Organic Chemistry Research: Researchers utilize it as a starting material or intermediate in multi-step synthesis projects, exploring novel chemical reactions and molecular designs.
  • Peptide and Amino Acid Chemistry: It can be incorporated into modified peptides or amino acid mimetics, introducing specific structural constraints or functionalities.

When considering the purchase of N-Cbz-4-Piperidinecarboxylic Acid, professionals often perform targeted searches such as 'buy N-Cbz-4-Piperidinecarboxylic acid,' 'CAS 10314-98-4 price,' or 'N-Cbz-4-Piperidinecarboxylic acid manufacturer.' This indicates a direct intent to procure the material for immediate use in research or production. The pricing of this chemical can vary based on purity, quantity, and supplier, with bulk purchasing often offering cost efficiencies.

For those seeking a reliable supplier, especially from regions known for robust chemical manufacturing like China, it is important to evaluate the manufacturer's track record, quality control processes, and customer service. A supplier that provides detailed technical data, responsive support, and consistent product availability is invaluable. Exploring options to 'purchase N-Cbz-4-Piperidinecarboxylic acid' from established chemical providers ensures that your laboratory or production facility receives material that meets the required specifications, thereby safeguarding the integrity and success of your synthesis projects.