Nicotinoyl Chloride Hydrochloride (CAS 20260-53-1) is a compound of significant interest across various scientific and industrial sectors, particularly in fine chemical synthesis and pharmaceutical development. A thorough understanding of its properties, safe handling practices, and application scope is essential for researchers, formulators, and procurement professionals. As a dedicated supplier and manufacturer, we aim to provide clear insights into this valuable chemical intermediate.

Physically, Nicotinoyl Chloride Hydrochloride typically presents as a white to off-white crystalline powder. Its molecular formula is C6H5Cl2NO, with a molecular weight of 178.02. A critical characteristic to note is its moisture sensitivity; it decomposes in the presence of water, necessitating careful storage and handling under anhydrous conditions. The melting point range is generally between 151-157 °C, providing a key parameter for quality assessment. Understanding these physical attributes is crucial when considering how to buy Nicotinoyl Chloride Hydrochloride and ensuring its stability throughout the supply chain.

Safety is paramount when working with any chemical reagent. Nicotinoyl Chloride Hydrochloride is classified with hazard pictograms, including GHS05, and carries a signal word of 'Danger.' It is known to cause severe skin burns and eye damage (H314). Therefore, appropriate personal protective equipment (PPE), such as gloves, eye protection, and protective clothing, must be worn when handling it. Proper ventilation and avoiding inhalation of dust are also critical safety measures. We advise all users to consult the Safety Data Sheet (SDS) for comprehensive handling and emergency procedures before use.

The applications of Nicotinoyl Chloride Hydrochloride are diverse and impactful. It is widely utilized as a key intermediate in the preparation of pharmaceuticals, especially for cardiovascular agents and renal drugs, owing to its derivative nature from nicotinic acid. Furthermore, it finds application in organic chemistry research for synthesizing various complex molecules and heterocycles. Its reactivity makes it a valuable tool for introducing the nicotinoyl group into target compounds, thereby facilitating the development of new materials and bioactive molecules. For those seeking to purchase this chemical, sourcing from a reliable manufacturer in China ensures access to a high-quality product with consistent specifications, backed by necessary documentation.