Nifuroxazide, identified by CAS number 965-52-6, is a pharmaceutical compound of significant interest for its potent antibacterial properties, particularly in treating gastrointestinal ailments. As a nitrofuran derivative, it plays a crucial role in managing conditions like acute diarrhea. For researchers and procurement specialists, understanding its mechanism, applications, and the best channels to buy Nifuroxazide is essential. This article explores these facets and provides insights for sourcing this vital chemical from manufacturers.

The Mechanism of Action: How Nifuroxazide Works

Nifuroxazide functions as an intestinal antiseptic and antibacterial agent. Its efficacy stems from its ability to interfere with critical bacterial enzyme systems. While the precise mechanisms are complex, it is understood that Nifuroxazide metabolizes into reactive intermediates within bacterial cells. These intermediates can damage bacterial DNA and inhibit protein synthesis, thereby halting bacterial growth and reproduction. This action is largely localized to the gastrointestinal tract, minimizing systemic absorption and associated side effects. It is known to have a broad spectrum of activity against common enteric pathogens, making it a valuable tool for combating bacterial diarrhea.

Clinical Applications of Nifuroxazide

The primary clinical application for Nifuroxazide (CAS 965-52-6) is the treatment of acute diarrhea. It is prescribed to reduce the bacterial load in the intestines, offering relief from symptoms associated with bacterial gastroenteritis. Its anti-inflammatory properties also contribute to its effectiveness, helping to reduce intestinal irritation and promote healing of the gut lining. While primarily used for diarrhea, research is ongoing into its potential in other areas, such as STAT3 inhibition for cancer treatment, highlighting its versatile pharmacological profile.

Sourcing High-Quality Nifuroxazide: A Procurement Guide

For pharmaceutical companies and research institutions, securing a reliable source of high-purity Nifuroxazide is paramount. When looking to purchase Nifuroxazide, it is crucial to select suppliers who guarantee adherence to international pharmaceutical standards, such as USP, BP, EP, and FCC. Manufacturers in China are significant producers of this compound, often offering competitive pricing for bulk orders. When making an inquiry, confirm the product's assay (typically ≥99% MIN), seek GMP and SGS certifications from the Nifuroxazide manufacturer, and request detailed technical data sheets.

Choosing the Right Nifuroxazide Supplier

Selecting the right Nifuroxazide supplier involves evaluating their manufacturing capabilities, quality control processes, and customer service. A reputable Nifuroxazide supplier will provide transparent information about their product and its origins. They should also be capable of handling diverse order sizes and offering logistical support. Many leading suppliers facilitate online inquiries, making it convenient to compare prices and specifications before committing to a purchase.

In summary, Nifuroxazide (CAS 965-52-6) is a critical antibacterial agent with well-established uses in treating diarrhea. Understanding its mechanism and ensuring you buy from a quality-assured manufacturer are key to successful procurement for pharmaceutical applications. Engaging with a trusted Nifuroxazide supplier in China can offer both quality and cost advantages.