O-Nitrobenzaldehyde, known scientifically by its CAS number 552-89-6, is a compound of significant industrial interest, particularly for its role in organic synthesis. Ningbo Inno Pharmchem Co., Ltd. highlights the importance of understanding its core properties and synthesis routes for effective industrial application.

Physically, O-Nitrobenzaldehyde presents as pale yellow crystalline powder. It possesses a characteristic benzaldehyde-like fragrance and is noted for its volatility with water vapor. Its melting point typically falls within the range of 42-44°C, with a boiling point recorded at 153°C at 23mm Hg. The compound exhibits good solubility in organic solvents such as ethanol, ether, and benzene, while its solubility in water is limited. From a safety perspective, it is noted that O-Nitrobenzaldehyde reacts vigorously with pyrrole and should be stored below +30°C, away from incompatible materials like strong oxidizers.

The synthesis of O-Nitrobenzaldehyde often starts from 2-nitrotoluene. One common method involves reacting 2-nitrotoluene with acetic anhydride, followed by hydrolysis. Another route includes the nitration and subsequent oxidation of 2-nitrotoluene. These methods are crucial for producing O-Nitrobenzaldehyde of the required purity for its downstream applications, ensuring its efficacy as a pharmaceutical intermediate and dye precursor.

Ningbo Inno Pharmchem Co., Ltd. emphasizes that the precise control over synthesis and purification processes is vital for delivering high-quality O-Nitrobenzaldehyde. This attention to detail ensures that the compound meets the stringent requirements of the pharmaceutical and dye industries, where consistency and purity are paramount. Understanding these properties and synthesis pathways allows industrial users to maximize the utility of O-Nitrobenzaldehyde in their respective manufacturing processes.