Oleoylethanolamide (OEA), chemically known as N-(2-Hydroxyethyl)oleamide (CAS 111-58-0), is an endogenous fatty acid amide that plays a crucial role in regulating energy balance and metabolism. As a high-affinity agonist for the peroxisome proliferator-activated receptor alpha (PPAR-α), OEA is recognized for its significant therapeutic potential, particularly in the treatment of obesity and arteriosclerosis.

For professionals in the pharmaceutical and life sciences industries, sourcing high-quality OEA is paramount. Understanding its properties and applications can guide your research and product development. This article delves into what makes OEA a compound of interest and how to secure a reliable supply.

The Science Behind Oleoylethanolamide (OEA)

OEA is synthesized in the small intestine in response to food intake, specifically fatty acids. Its primary mechanism of action involves binding to and activating PPAR-α, a nuclear receptor that regulates genes involved in lipid metabolism, fatty acid oxidation, and inflammation. This activation leads to several beneficial physiological effects:

  • Appetite Regulation: OEA signals satiety to the brain, reducing food intake and promoting weight loss.
  • Lipid Metabolism: It enhances fatty acid oxidation in tissues like the liver and muscle, lowering triglyceride levels and improving cholesterol profiles.
  • Anti-inflammatory Effects: By modulating inflammatory pathways, OEA can contribute to managing conditions like arteriosclerosis.

The chemical structure of Oleoylethanolamide, C20H39NO2, with a molecular weight of 325.52900, contributes to its biological activity. Its physical form is typically a white to off-white solid, with a melting point range of 50-60°C, making it manageable for formulation.

Sourcing High-Purity OEA: A Manufacturer's Perspective

When seeking to buy Oleoylethanolamide for pharmaceutical research or therapeutic development, purity and consistency are non-negotiable. As a dedicated Oleoylethanolamide manufacturer, we understand the stringent requirements of the industry. We specialize in producing OEA with a purity of ≥98%, ensuring that your experiments and formulations are based on reliable compounds. Our commitment as an OEA supplier in China is to provide researchers and formulators with a product that meets international quality standards.

For those looking for an Oleoylethanolamide price that reflects both quality and value, partnering with a direct manufacturer offers significant advantages. We can ensure a stable supply chain, crucial for ongoing research projects and the eventual commercialization of OEA-based therapeutics. Whether you are developing new obesity treatments or seeking to mitigate arteriosclerosis, our high-purity N-(2-Hydroxyethyl)oleamide is an essential component.

How to Purchase Oleoylethanolamide

To procure Oleoylethanolamide, it is advisable to work with established manufacturers and suppliers who can provide detailed specifications, Certificates of Analysis (CoA), and robust customer support. When you buy Oleoylethanolamide, consider the supplier's experience in producing pharmaceutical intermediates. Our company stands as a testament to reliable sourcing, offering competitive OEA pricing and efficient delivery worldwide.

Investing in high-quality Oleoylethanolamide from a trusted manufacturer in China is a strategic step towards advancing your research and product development in metabolic health. We invite you to contact us to learn more about our Oleoylethanolamide products and how we can support your pharmaceutical endeavors.