Oxtriphylline, identified by CAS number 4499-40-5 and also known as choline theophyllinate, is a significant compound in the field of respiratory medicine. As a leading Oxtriphylline manufacturer, we are dedicated to providing high-quality material for various pharmaceutical applications. This article delves into the chemical and pharmacological aspects of Oxtriphylline, offering insights relevant to R&D scientists and formulators.

Chemically, Oxtriphylline is the choline salt of theophylline. Its molecular formula is C₁₂H₂₁N₅O₃, with a molecular weight of approximately 283.33 g/mol. It typically presents as a white crystalline powder. The compound is derived from xanthine, a purine base, and its therapeutic action is primarily attributed to the release of theophylline within the body.

The pharmacological mechanism of Oxtriphylline centers on the actions of theophylline. Theophylline acts as a non-selective phosphodiesterase (PDE) inhibitor. PDEs are enzymes that break down cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). By inhibiting these enzymes, Oxtriphylline indirectly increases intracellular cAMP levels in smooth muscle cells. This elevation in cAMP leads to the relaxation of bronchial smooth muscles, resulting in bronchodilation and improved airflow. This action is crucial for treating conditions like asthma, chronic bronchitis, and emphysema.

Furthermore, theophylline also functions as an adenosine receptor antagonist. Adenosine can cause bronchoconstriction, so blocking its receptors further contributes to the bronchodilatory effects of Oxtriphylline. Additionally, it can affect calcium flux and intracellular calcium distribution, modulate inflammatory responses by reducing the production of inflammatory mediators, and enhance diaphragmatic contractility, aiding in lung capacity.

For those looking to buy Oxtriphylline, understanding its properties is key. As a reliable Oxtriphylline supplier in China, we ensure our product meets stringent purity requirements, typically exceeding 98%. We provide detailed specifications and support for R&D purposes. When considering bulk purchase, inquiring about Oxtriphylline price China will reveal our competitive offerings for this essential pharmaceutical intermediate.

In essence, Oxtriphylline is a pharmacologically active compound with a well-defined mechanism for respiratory relief. Partnering with a reputable pharmaceutical grade Oxtriphylline manufacturer ensures you receive a product that can confidently be incorporated into your formulation development and production pipelines.