In the complex world of pharmaceutical research and chemical synthesis, understanding the properties and sourcing of key compounds is crucial. Pemetrexed Acid, identified by CAS number 137281-23-3, is a significant chemical entity, primarily recognized as N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid. This compound serves as a vital pharmaceutical intermediate, underpinning the development of important therapeutic agents. For procurement specialists and researchers, a thorough understanding of Pemetrexed Acid, including its characteristics and how to acquire it, is essential.

Pemetrexed Acid is characterized by its intricate molecular structure, featuring a pyrrolo[2,3-d]pyrimidine core linked to a benzoyl-L-glutamic acid moiety. This structure confers its potent biological activity as an antifolate. It acts by inhibiting key enzymes in the folate pathway, which are indispensable for DNA and RNA synthesis. This inhibitory action makes it a critical component in the research and production of antineoplastic agents. Its typical form is a solid powder, and its purity is a paramount concern for all downstream applications.

When considering where to buy Pemetrexed Acid, it is vital to engage with reliable and reputable suppliers. The quality of Pemetrexed Acid directly impacts the efficacy and safety of the final pharmaceutical products. Therefore, looking for suppliers who provide detailed specifications, including purity assays (often via HPLC) and structural confirmations (e.g., NMR, MS), is a standard practice. Many leading suppliers also offer Pemetrexed Acid with a CAS number of 137281-23-3, ensuring proper identification and traceability. For buyers seeking cost-effectiveness, exploring options from a dedicated manufacturer in China can be advantageous, often providing competitive Pemetrexed Acid price points for bulk quantities.

The procurement process involves more than just finding a product listing. It requires establishing a relationship with a supplier who understands the demands of the pharmaceutical industry. This includes ensuring timely delivery, providing proper documentation (such as Certificates of Analysis), and offering responsive customer service. Whether you need laboratory-scale quantities for research or bulk volumes for manufacturing, selecting a supplier who can meet your specific requirements is crucial. The availability of Pemetrexed Acid from established chemical companies ensures that research and development efforts can proceed without interruption.

In summary, Pemetrexed Acid is a cornerstone intermediate in pharmaceutical synthesis. Understanding its properties, prioritizing quality from trusted suppliers, and considering competitive pricing are all essential steps for any organization looking to purchase this compound. Partnering with a knowledgeable and reliable supplier is key to ensuring the success of your projects involving this critical pharmaceutical ingredient.