In the complex world of chemical manufacturing, understanding the properties and applications of key intermediates is vital for scientific advancement and commercial success. Phenethyl Isocyanate (CAS 1943-82-4) is one such compound, playing a crucial role, particularly within the pharmaceutical sector. This guide aims to provide R&D scientists, formulators, and procurement specialists with a thorough overview of Phenethyl Isocyanate, covering its essential characteristics, primary uses, and best practices for sourcing.

Phenethyl Isocyanate, with the CAS number 1943-82-4, is chemically known as 2-phenylethyl isocyanate. It is typically supplied as a colorless to light-yellow liquid. Its molecular formula is C9H9NO, and it possesses a pungent odor. A key attribute is its purity, which commonly reaches 98% or higher, making it suitable for demanding synthesis applications. The compound is sensitive to moisture, a characteristic that dictates careful handling and storage conditions to maintain its integrity and reactivity.

The predominant application for Phenethyl Isocyanate is its use as a crucial intermediate in the synthesis of glimepiride. Glimepiride is a highly effective oral anti-diabetic drug belonging to the sulfonylurea class, widely prescribed for managing type 2 diabetes. The precise chemical structure and high purity of Phenethyl Isocyanate are essential for achieving the desired yield and quality of glimepiride. Therefore, companies involved in the production of this drug must ensure a consistent and reliable supply of this intermediate.

For those looking to purchase Phenethyl Isocyanate, identifying a reputable manufacturer is key. Suppliers from regions like China are often competitive in offering high-quality chemical intermediates. When evaluating potential suppliers, it is important to look for manufacturers that provide comprehensive product specifications, detailed safety data (MSDS), and certificates of analysis (COA). These documents are critical for quality control and regulatory compliance in pharmaceutical production. Terms like 'buy Phenethyl Isocyanate' or 'Phenethyl Isocyanate manufacturer' will guide your search for reliable partners.

Beyond its primary role in glimepiride synthesis, Phenethyl Isocyanate serves as a valuable reagent in broader organic chemistry. It can be used to create diverse sulfonamide derivatives with potential pharmacological activities. This versatility makes it an interesting compound for academic research and early-stage drug discovery projects. The demand for such intermediates is sustained by the continuous innovation within the pharmaceutical and fine chemical industries.

In conclusion, Phenethyl Isocyanate (CAS 1943-82-4) is a significant chemical intermediate with critical applications in pharmaceutical manufacturing, particularly for anti-diabetic drugs. Understanding its properties, ensuring its purity, and partnering with reliable manufacturers are essential steps for any organization seeking to procure this vital compound.