Understanding Pinacol (CAS 76-09-5): Properties and Synthesis
For professionals in the chemical industry, a thorough understanding of core chemical compounds is fundamental. Pinacol, scientifically known as 2,3-dimethylbutane-2,3-diol and bearing the CAS number 76-09-5, is one such compound. This organic molecule is characterized by its appearance as a white crystalline solid and its classification as a vicinal diol, meaning it possesses two hydroxyl (-OH) groups on adjacent carbon atoms.
Key physicochemical properties of Pinacol include a melting point typically ranging from 40-43°C, making it a low-melting solid at room temperature. It exhibits good solubility in hot water, alcohol, and diethyl ether, which is advantageous for various reaction and purification processes. Its molecular formula is C6H14O2, with a molecular weight of 118.17 g/mol. The molecule's structure, featuring two tertiary alcohol groups, dictates its chemical behavior, most notably its susceptibility to the pinacol rearrangement under acidic conditions.
The synthesis of Pinacol is commonly achieved through the bimolecular reduction of acetone. This process, often involving reducing agents, leads to the coupling of two acetone molecules to form the stable 1,2-diol structure of Pinacol. Understanding these synthesis routes is crucial for manufacturers aiming to produce Pinacol efficiently and cost-effectively.
As a critical intermediate, Pinacol is widely used in organic synthesis, particularly in the preparation of organoboron compounds essential for cross-coupling reactions in pharmaceutical and materials science research. Its purity is a critical factor, with specifications often requiring ≥99% assay. For those looking to buy Pinacol, consulting with chemical suppliers regarding these detailed properties and the consistency of their product is advisable.
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“Pinacol, scientifically known as 2,3-dimethylbutane-2,3-diol and bearing the CAS number 76-09-5, is one such compound.”