For manufacturers across various industries, understanding the fundamental properties and diverse applications of key chemical components is essential for product innovation and quality assurance. Poloxamer 407, a versatile non-ionic surfactant, offers a unique combination of characteristics that make it valuable in sectors ranging from pharmaceuticals and cosmetics to industrial coatings and research. As a leading manufacturer and supplier of Poloxamer 407 in China, we aim to provide clarity on this crucial ingredient for your business needs.

Poloxamer 407 is a triblock copolymer comprising a central hydrophobic block of polypropylene glycol (PPG) and two flanking hydrophilic blocks of polyethylene glycol (PEG). This amphiphilic structure dictates its surfactant behavior, enabling it to reduce surface tension and act as an emulsifier, solubilizer, and dispersant. The ratio and length of these blocks can be varied to create different poloxamer grades, with Poloxamer 407 being one of the most widely used due to its balanced properties. For manufacturers looking to buy this material, understanding its CAS number (9003-11-6) and its precise chemical structure is the first step.

Beyond its surfactant capabilities, Poloxamer 407 is particularly noted for its thermogelling behavior in aqueous solutions. At concentrations typically above 20-30% by weight, it forms a clear, viscous solution at low temperatures that transitions into a stable gel upon warming to body temperature or slightly above. This unique property has found significant applications in controlled drug delivery, where it can encapsulate active ingredients and release them gradually as the gel dissolves or degrades. If your company is exploring such applications, sourcing Poloxamer 407 from a reliable manufacturer is paramount for consistent performance.

The applications for Poloxamer 407 are extensive. In the pharmaceutical industry, it serves as an approved excipient in various formulations. In cosmetics, it’s used in creams, lotions, and cleaning solutions. Its utility also extends to bioprinting as a sacrificial support material and in other industrial sectors requiring effective emulsification or dispersion. When considering your procurement strategy, comparing the price and quality from different Poloxamer 407 suppliers is advisable. We, as a dedicated manufacturer, offer competitive pricing and ensure the high purity and quality demanded by discerning industrial clients. Let us be your go-to source for Poloxamer 407.