Polysorbate 20, scientifically identified by its CAS number 9005-64-5, is a widely utilized nonionic surfactant that plays a crucial role across a multitude of industries. Its unique chemical structure, derived from sorbitol and lauric acid, bestows upon it remarkable properties as an emulsifier, solubilizer, detergent, and wetting agent. This article provides an overview of Polysorbate 20, its manufacturing, key characteristics, and broad industrial applications, along with insights into sourcing it from reliable chemical manufacturers.

The synthesis of Polysorbate 20 involves a two-step process. First, sorbitan is ethoxylated, meaning it reacts with ethylene oxide to form a polyoxyethylene chain. The '20' in its nomenclature indicates that, on average, twenty moles of ethylene oxide are added. Subsequently, this ethoxylated sorbitan is esterified with lauric acid, a common fatty acid. This chemical engineering results in a molecule that is amphiphilic – possessing both hydrophilic (water-loving) and hydrophobic (oil-loving) regions. This amphiphilic nature is the foundation of its surfactant capabilities.

Key properties of Polysorbate 20 include its status as a viscous liquid, typically light yellow in color. Its molecular formula is C26H50O10, with a molecular weight of approximately 522.6692 g/mol. Its relative nontoxicity and excellent stability under various conditions make it a preferred choice for formulators aiming for safe and effective products.

The applications of Polysorbate 20 are remarkably diverse. In the pharmaceutical industry, it serves as an essential excipient for solubilizing poorly water-soluble APIs, stabilizing emulsions in topical and oral preparations, and acting as a dispersing agent. For procurement teams, identifying a trusted 'Polysorbate 20 manufacturer' that can guarantee high purity (e.g., 99% min) is critical for pharmaceutical-grade products.

In the cosmetic and personal care sector, Polysorbate 20 is indispensable. It functions as an emulsifier in lotions and creams, a solubilizer for fragrances and essential oils in perfumes, and a cleansing agent in shampoos and body washes. The demand for consistent quality drives formulators to seek reliable 'Polysorbate 20 suppliers'.

The food industry utilizes Polysorbate 20 as an emulsifier and stabilizer, contributing to the texture and stability of products such as dressings, baked goods, and confectionery. Its GRAS (Generally Recognized As Safe) status in many regions underscores its safety for food applications.

Additionally, Polysorbate 20 finds use in scientific research as a buffer component, a stabilizer in biological assays, and in diagnostic kits. Its detergent properties are also leveraged in various industrial cleaning applications.

When considering the purchase of Polysorbate 20, it is advisable to look for 'wholesale Polysorbate 20' from established manufacturers, particularly in regions like China, known for their extensive chemical production capabilities. Engaging with these suppliers often provides competitive 'Polysorbate 20 price' points and the opportunity to obtain 'free samples' for quality verification. A thorough review of the manufacturer's certifications and adherence to industry standards is recommended.

In summary, Polysorbate 20 (CAS 9005-64-5) is a highly versatile and critical chemical intermediate. Its broad applicability across pharmaceutical, cosmetic, food, and industrial sectors highlights its significance. Strategic sourcing from reputable manufacturers ensures the availability of high-quality Polysorbate 20, which is fundamental for product development and success.