Praziquantel is a crucial compound in the fight against parasitic worm infections, particularly schistosomiasis and tapeworm infestations. For B2B buyers in the pharmaceutical, chemical, and veterinary sectors, understanding the nuances of Praziquantel, from its mechanism of action to its market procurement, is vital. This article aims to provide procurement managers, R&D scientists, and formulators with a comprehensive overview of Praziquantel, highlighting its critical role and offering insights into sourcing high-quality material.

Mechanism of Action and Therapeutic Applications

Praziquantel, typically supplied as a white to almost white crystalline powder with the CAS number 55268-74-1, functions by disrupting the parasite's calcium homeostasis. It increases the permeability of cell membranes to calcium ions, leading to rapid and sustained muscle contractions and vacuolization of the parasite's tegument. This paralysis dislodges the worms, making them susceptible to the host's immune system or expulsion. Its broad-spectrum activity makes it the drug of choice for treating various fluke and tapeworm infections in both humans and animals. For buyers, knowing that a reputable Praziquantel supplier provides material with >99% purity ensures optimal therapeutic efficacy.

Quality and Sourcing: A Procurement Manager's Guide

When you need to buy Praziquantel, several factors must be considered to ensure you are obtaining a quality product from a reliable source. As a pharmaceutical intermediate, Praziquantel's purity is paramount. Look for manufacturers that adhere to strict quality control measures and provide certifications such as ISO 9001, USP, and BP. The chemical's appearance (white crystalline powder) and its CAS number (55268-74-1) are standard identifiers. Procuring from a qualified Praziquantel manufacturer in China can offer significant advantages in terms of scale and cost-effectiveness. It is advisable to request a detailed product specification sheet and a sample for internal testing before committing to a large purchase.

Market Dynamics and Procurement Strategies

  • Praziquantel Price Benchmarking: Understanding the prevailing Praziquantel price for sale requires market research. Factors influencing price include raw material costs, production capacity, and global demand. Bulk orders often command better pricing.
  • Supplier Relationship Management: Building strong relationships with your chosen suppliers ensures continuity of supply and can lead to better service and pricing over time.
  • Logistics and Delivery: Given its use as an intermediate, timely delivery is crucial. A reliable supplier will offer various shipping options and transparent delivery timelines.
  • Technical Support: Reputable manufacturers often provide technical support, assisting with product application and troubleshooting.

The Importance of Praziquantel in Global Health Initiatives

Praziquantel is listed on the World Health Organization's List of Essential Medicines, underscoring its importance in public health. Its effectiveness and relatively good safety profile make it a cornerstone treatment for neglected tropical diseases like schistosomiasis. For organizations involved in these initiatives, securing a stable supply of high-quality Praziquantel is critical. A dependable Praziquantel supplier is not just a vendor but a partner in advancing global health outcomes.

In conclusion, Praziquantel (CAS 55268-74-1) is a vital pharmaceutical intermediate with significant therapeutic applications. Procurement managers and R&D professionals should prioritize high purity (>99%), seek certified suppliers, and understand market pricing to ensure the successful integration of this compound into their products. By making informed sourcing decisions, businesses can contribute to effective parasitic disease management worldwide.