For procurement professionals and R&D scientists in the chemical and pharmaceutical industries, understanding the pricing dynamics of key intermediates is crucial for budgeting and strategic sourcing. (S)-tert-butyl 3-oxo-1-phenylpropylcarbamate (CAS 135865-78-0), a valuable chiral building block, is often sourced from China, a global hub for chemical manufacturing. This article delves into the factors that influence the price of this compound when purchased from Chinese manufacturers and suppliers.

The primary determinant of price for (S)-tert-butyl 3-oxo-1-phenylpropylcarbamate is, naturally, its production cost. This includes the cost of raw materials, energy, labor, and the complexity of the synthesis process itself. As a chiral intermediate, its synthesis requires specific stereochemical control, which can add to the production complexity and, consequently, the price. Manufacturers invest in advanced synthesis technologies and skilled personnel to ensure the required enantiomeric purity, directly impacting the cost.

Scale of production is another significant factor. When a buyer is looking to purchase CAS 135865-78-0 in bulk quantities, manufacturers can leverage economies of scale. This often leads to a lower price per kilogram compared to smaller, research-scale orders. Manufacturers with large production capacities are better positioned to offer competitive pricing for high-volume requirements, making them attractive partners for established pharmaceutical companies.

Market demand and supply also play a pivotal role. If (S)-tert-butyl 3-oxo-1-phenylpropylcarbamate is a critical intermediate for a widely used pharmaceutical, such as Maraviroc, then increased demand can put upward pressure on prices. Conversely, an oversupply or the emergence of more efficient synthesis routes can lead to price reductions. Buyers should stay informed about market trends and maintain open communication with their suppliers regarding future demand forecasts.

When considering the price from Chinese manufacturers, it's essential to look beyond just the per-unit cost. Factors like shipping costs, import duties, and currency exchange rates will also influence the final landed price. Reputable suppliers will provide clear pricing structures, including shipping options and estimated delivery times. For those looking to buy this intermediate, engaging with several Chinese chemical manufacturers and requesting detailed quotes will provide a comprehensive understanding of the current market price for (S)-tert-butyl 3-oxo-1-phenylpropylcarbamate.