Understanding the Properties of 3-Hydroxytetrahydrofuran for Chemical Formulations
In the realm of chemical manufacturing and research, a deep understanding of a compound's properties is fundamental to its effective application. 3-Hydroxytetrahydrofuran (CAS 453-20-3), a cyclic ether with a hydroxyl functional group, offers a unique set of characteristics that make it valuable in a variety of synthesis and formulation processes. This exploration focuses on its key physical and chemical attributes and their implications for industrial use.
Primarily, 3-Hydroxytetrahydrofuran is described as a clear, colorless to yellow liquid. This visual characteristic is often a first indicator of its purity. Its boiling point is consistently reported around 181°C, a moderately high temperature that suggests it can withstand processing conditions that require moderate heating without significant decomposition. The density of approximately 1.09 g/mL at 25°C indicates it is slightly denser than water, a property that can be relevant in phase separations and solvent mixtures.
Chemically, the presence of the hydroxyl group makes 3-Hydroxytetrahydrofuran a nucleophile and a potential hydrogen bond donor/acceptor. This allows it to participate in a wide array of reactions, including esterification, etherification, and reactions with electrophilic reagents. The stability of the tetrahydrofuran ring provides a robust structure that can be maintained through many synthetic transformations.
For researchers and formulators, understanding its stability and incompatibilities is crucial. Sources indicate that 3-Hydroxytetrahydrofuran is stable under normal conditions but incompatible with strong oxidizing agents, acid chlorides, and acid anhydrides. This information is vital for safe handling, storage, and reaction design, especially when one is looking to buy or utilize this compound for specific chemical applications.
The compound's polarity, derived from both the ether oxygen and the hydroxyl group, contributes to its solubility in water and various organic solvents. This makes it a versatile choice as a reaction medium or a component in formulated products where miscibility is important. When seeking to procure 3-Hydroxytetrahydrofuran, paying attention to the detailed technical data provided by manufacturers is essential for ensuring it meets the precise requirements of your application.
Procurement professionals and R&D chemists often search for '3-Hydroxytetrahydrofuran properties' or 'CAS 453-20-3 technical data' to gather this information. Understanding these properties helps in selecting the right supplier and ensuring the optimal use of the chemical, whether for pharmaceutical synthesis, agrochemical development, or other fine chemical applications. If you are looking to purchase this intermediate, consider manufacturers who offer comprehensive technical support and high-purity products.
Perspectives & Insights
Agile Reader One
“09 g/mL at 25°C indicates it is slightly denser than water, a property that can be relevant in phase separations and solvent mixtures.”
Logic Vision Labs
“Chemically, the presence of the hydroxyl group makes 3-Hydroxytetrahydrofuran a nucleophile and a potential hydrogen bond donor/acceptor.”
Molecule Origin 88
“This allows it to participate in a wide array of reactions, including esterification, etherification, and reactions with electrophilic reagents.”