At NINGBO INNO PHARMCHEM CO.,LTD., we emphasize the critical properties that make 1-(4-Iodophenyl)-2-Piperidinone an essential pharmaceutical intermediate. With the CAS number 385425-15-0, this compound is a cornerstone in the chemical synthesis of Apixaban, a vital antithrombotic drug. Understanding its physical and chemical characteristics is key to appreciating its utility in advanced pharmaceutical manufacturing.

The compound's molecular formula is C11H12INO, with a molecular weight of 301.12400. Its appearance as a white to off-white crystalline powder, combined with stringent specifications such as a purity of ≥98.5% (HPLC), single impurity ≤0.5%, total impurity ≤1.0%, and moisture content ≤0.5%, underscores its suitability for pharmaceutical applications. These parameters are critical for ensuring the efficacy and safety of the final drug product. The density of 1.670 g/cm³, a melting point of 118-120°C, and a boiling point of 446.1°C indicate its stability and handling characteristics within typical chemical synthesis environments. These specifications are what make NINGBO INNO PHARMCHEM CO.,LTD. a trusted 1-(4-Iodophenyl)-2-Piperidinone supplier in China.

The primary application of 1-(4-Iodophenyl)-2-Piperidinone is its role as a crucial intermediate in the synthesis of Apixaban. Apixaban functions by inhibiting Factor Xa, thereby preventing the formation of blood clots and reducing the risk of stroke and systemic embolism in patients with conditions like atrial fibrillation or those who have undergone hip or knee replacement surgery. The demand for such life-saving medications drives the need for efficient and scalable production of their intermediates. Our expertise as a pharmaceutical intermediate manufacturer in China ensures that we can meet this demand consistently.

The synthesis of this intermediate, typically involving 4-Iodoaniline and 5-Bromovaleryl Chloride, highlights the sophisticated processes employed in fine chemical production. For pharmaceutical companies seeking a reliable 1-(4-Iodophenyl)-2-Piperidinone manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. offers a combination of quality, consistency, and advanced production capabilities. We are dedicated to supporting the pharmaceutical industry by providing high-quality intermediates that contribute to the development of essential medicines.