Understanding the Properties and Applications of 1-Boc-1-methylhydrazine (CAS 21075-83-2)
In the intricate world of chemical manufacturing, certain compounds serve as linchpins for producing advanced materials and pharmaceuticals. 1-Boc-1-methylhydrazine, identified by its CAS number 21075-83-2, is one such critical molecule. As a derivative of hydrazine, it features a tert-butoxycarbonyl (Boc) protecting group, which is frequently employed in organic synthesis to temporarily block a functional group, thus allowing other reactions to proceed selectively. This characteristic makes it an invaluable pharmaceutical raw material.
The chemical identity of 1-Boc-1-methylhydrazine is defined by its molecular formula, C6H14N2O2, and a molecular weight of approximately 146.19 g/mol. Its physical properties, such as being a colorless to almost colorless liquid with a density of 0.985 g/mL at 25°C and a boiling point of 186°C, are important considerations for its handling and use in laboratory and industrial settings. The compound also possesses a flash point of 71°C, indicating specific safety precautions that must be taken during storage and use.
The primary application of 1-Boc-1-methylhydrazine lies in its role as an intermediate for synthesizing complex pharmaceutical compounds. Notably, it is used in the preparation of alamolin, a ghrelin receptor agonist developed for treating anorexia and cachexia. This makes it a crucial component in the development of therapies for conditions that cause significant metabolic distress. The synthesis pathways involving this compound are carefully designed to leverage its reactive sites and protecting group strategically. For those seeking to buy 1-Boc-1-methylhydrazine, understanding its precise applications is key to ensuring its effective integration into their research or production processes.
The broader significance of 1-Boc-1-methylhydrazine extends to its utility as a general research chemical in organic synthesis. Its structure allows for diverse chemical transformations, making it a versatile tool for chemists exploring new molecular entities. The consistent quality and availability of N-Boc-N-methylhydrazine from reputable suppliers are essential for reproducible scientific outcomes. Manufacturers specializing in pharmaceutical intermediates manufacturing often feature this compound in their catalogs, catering to the needs of drug discovery and development labs.
In summary, 1-Boc-1-methylhydrazine (CAS 21075-83-2) is an important chemical entity with well-defined properties and critical applications in the pharmaceutical industry. Its role as a precursor in the synthesis of drugs like alamolin highlights its value in advancing medical treatments. Whether for large-scale production or cutting-edge research, this compound remains a cornerstone in the field of organic and pharmaceutical chemistry.
Perspectives & Insights
Core Pioneer 24
“985 g/mL at 25°C and a boiling point of 186°C, are important considerations for its handling and use in laboratory and industrial settings.”
Silicon Explorer X
“The compound also possesses a flash point of 71°C, indicating specific safety precautions that must be taken during storage and use.”
Quantum Catalyst AI
“The primary application of 1-Boc-1-methylhydrazine lies in its role as an intermediate for synthesizing complex pharmaceutical compounds.”