For chemists and R&D professionals, a deep understanding of chemical intermediates is fundamental to innovation. 2,6-Dimethylmorpholine (CAS 141-91-3) is one such compound that offers significant versatility in organic synthesis. Known for its specific physical and chemical properties, it serves as a valuable building block in both pharmaceutical and agrochemical industries. Exploring these characteristics helps scientists and procurement managers identify its potential applications and source it effectively from reliable manufacturers.

Key Physical and Chemical Properties of 2,6-Dimethylmorpholine

2,6-Dimethylmorpholine typically presents as a colorless to light brown liquid. Its molecular formula is C6H13NO, with a molecular weight of 115.174. Key physical parameters include a boiling point of approximately 146.6°C at 760 mmHg and a melting point of -85°C, indicating it remains liquid under standard laboratory conditions. The flash point is around 48.9°C, and its vapor pressure is noted as 4.6±0.2 mmHg at 25°C, providing important safety and handling information for users. The refractive index is approximately 1.406. The compound's purity is generally specified as ≥98.0%, making it suitable for demanding synthetic procedures. These properties, combined with its chemical reactivity, make it a sought-after intermediate for custom synthesis and product development.

Applications in Synthesis and Manufacturing

The primary application of 2,6-Dimethylmorpholine lies in its role as an intermediate in the synthesis of more complex molecules. Its most prominent use is in the production of Fenpropimorph (CAS 67306-03-0), a crucial fungicide in agriculture. Beyond this, it is utilized in the pharmaceutical industry as a building block for various active pharmaceutical ingredients (APIs). Researchers often leverage its structure to introduce specific stereochemical features or functional groups into target molecules. When considering purchasing this chemical, R&D scientists should look for suppliers that offer consistent quality and availability, ideally from manufacturers in regions like China, where large-scale production is common and competitive pricing can be secured. Understanding the CAS number, 141-91-3, is essential for accurate identification and procurement.

Sourcing Strategies and Supplier Selection

For companies looking to buy 2,6-Dimethylmorpholine, the selection of a reliable supplier is paramount. Key criteria include the supplier's manufacturing capabilities, quality control processes, and customer service. Manufacturers that can provide detailed specifications, such as the physical properties mentioned above, along with a Certificate of Analysis (CoA), are generally preferred. Procurement managers should not hesitate to request quotes and samples to evaluate the product and supplier's responsiveness. Establishing a relationship with a trusted chemical manufacturer ensures a steady supply chain, which is critical for ongoing research and commercial production. Many global buyers find value in sourcing from established Chinese manufacturers for their cost-effectiveness and production capacity.

In summary, 2,6-Dimethylmorpholine is a valuable intermediate with well-defined properties that facilitate its use in critical synthesis pathways. By understanding its characteristics and engaging with reputable suppliers, chemical professionals can effectively utilize this compound to drive innovation in their respective fields.