For professionals working in the chemical and pharmaceutical industries, a thorough understanding of compound properties is fundamental to successful research and manufacturing. Ethyl Indole-2-carboxylate, bearing the CAS number 3770-50-1, is a significant heterocyclic compound whose properties make it a valuable intermediate. This article aims to provide a comprehensive overview of its characteristics, applications, and how to source it effectively.

Ethyl Indole-2-carboxylate, with the molecular formula C11H11NO2 and a molecular weight of 189.21, is an ester derivative of indole-2-carboxylic acid. Its physical appearance is typically described as a white to off-white crystalline powder, with a melting point that commonly falls between 119-126°C. These properties suggest it is a stable compound under normal laboratory conditions, making it suitable for handling and storage. When you need to buy this chemical, ensuring these specifications are met is crucial for process reliability.

The chemical reactivity of Ethyl Indole-2-carboxylate is largely dictated by the indole ring system and the ester group. The ester can undergo reactions such as hydrolysis to form the corresponding carboxylic acid, or it can be reduced to an alcohol. The indole nitrogen can be alkylated or acylated, and the aromatic ring system can participate in electrophilic substitution reactions. These versatile reaction pathways make it an important building block for creating more complex molecules used in pharmaceuticals and fine chemicals.

The primary application of Ethyl Indole-2-carboxylate is as a pharmaceutical intermediate. The indole scaffold is a privileged structure in medicinal chemistry, found in numerous approved drugs targeting a wide array of diseases. Therefore, when researchers or manufacturers look to buy this compound, they are often seeking to incorporate this core structure into potential drug candidates. Beyond pharmaceuticals, it also finds use in agrochemical synthesis and as a general reagent in organic chemistry laboratories.

When considering the purchase of CAS 3770-50-1, it is essential to partner with reputable manufacturers or suppliers who can guarantee consistent purity, often cited as 97% or higher. Verifying the supplier's quality control measures and requesting lot-specific Certificates of Analysis are standard practices. Understanding the price point for Ethyl Indole-2-carboxylate is also part of the procurement process, and comparing offers from different suppliers, especially those based in China, can lead to cost savings without compromising quality.

In summary, Ethyl Indole-2-carboxylate (CAS 3770-50-1) is a chemically significant compound with well-defined properties and diverse applications, particularly as a pharmaceutical intermediate. Professionals seeking to buy this chemical should prioritize quality, purity, and supplier reliability to ensure successful outcomes in their synthetic projects.