In the realm of chemical synthesis, understanding the nuanced properties of key intermediates is fundamental to successful research and development. 4-Hydroxy-6-(trifluoromethyl)pyrimidine (CAS: 1546-78-7) is a prime example of such a compound, offering unique characteristics that make it invaluable for a wide array of synthetic applications. As a leading supplier, NINGBO INNO PHARMCHEM is committed to providing this high-purity chemical intermediate to researchers and manufacturers worldwide. This article explores the properties of 4-Hydroxy-6-(trifluoromethyl)pyrimidine and its diverse applications in modern chemistry.

Chemical Structure and Properties Overview

4-Hydroxy-6-(trifluoromethyl)pyrimidine is characterized by its heterocyclic pyrimidine ring, functionalized with a hydroxyl group and a trifluoromethyl substituent. This structural combination results in specific electronic and reactivity profiles. The presence of the electron-withdrawing trifluoromethyl group influences the acidity of the hydroxyl proton and the reactivity of the ring system. Typically appearing as a white solid, its purity, often exceeding 99% by HPLC, is a critical parameter for its effective use in sensitive synthetic procedures. For chemists looking to buy 4-Hydroxy-6-(trifluoromethyl)pyrimidine, understanding these properties ensures appropriate handling and application.

Diverse Synthesis Applications

The versatility of 4-Hydroxy-6-(trifluoromethyl)pyrimidine is evident in its broad spectrum of applications across different fields of chemistry:

  • Organic Synthesis: It serves as a crucial building block for constructing complex organic molecules. The hydroxyl group can be readily transformed through various reactions such as O-alkylation, O-acylation, or nucleophilic aromatic substitution, allowing for the introduction of diverse functional groups.
  • Pharmaceutical Intermediates: In medicinal chemistry, this compound is instrumental in synthesizing potential drug candidates. Its fluorinated nature can enhance metabolic stability and bioavailability, making it a valuable component in drug discovery pipelines. Procurement managers often search for a reliable 4-Hydroxy-6-(trifluoromethyl)pyrimidine supplier for these purposes.
  • Agrochemical Development: The unique properties imparted by the trifluoromethyl group also make it useful in the development of new agrochemicals, contributing to advancements in crop protection and yield enhancement.
  • Material Science: Researchers may also find applications for this intermediate in developing novel functional materials due to its specific chemical structure and reactivity.

Sourcing High-Quality Intermediates

When procuring such specialized chemicals, selecting a dependable 4-Hydroxy-6-(trifluoromethyl)pyrimidine manufacturer is paramount. NINGBO INNO PHARMCHEM, as a leading producer and supplier, ensures that our 4-Hydroxy-6-(trifluoromethyl)pyrimidine meets the highest purity standards. We offer competitive 4-Hydroxy-6-(trifluoromethyl)pyrimidine price points, making advanced chemical synthesis accessible. By choosing us, you ensure a stable supply of high-quality intermediates for your critical research and production needs.

For your next synthesis project, rely on NINGBO INNO PHARMCHEM for your supply of 4-Hydroxy-6-(trifluoromethyl)pyrimidine. Contact us to learn more and get a quote.