For organic chemists and material scientists, a deep understanding of chemical intermediates is fundamental to successful synthesis. 2-Bromo-3-chlorothiophene (CAS 77893-68-6) is one such compound that offers significant synthetic utility due to its specific chemical structure and reactivity. As a seasoned chemical intermediate manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing clear, actionable information for professionals looking to leverage this compound.

Chemical Profile of 2-Bromo-3-chlorothiophene

2-Bromo-3-chlorothiophene, identified by CAS 77893-68-6, boasts a molecular formula of C4H2BrClS and a molecular weight of 197.481. Key physical properties include a boiling point of approximately 202.5±20.0 °C at 760 mmHg and a density of 1.8±0.1 g/cm³. Typically appearing as a colorless to yellowish liquid, its precise properties are critical for reaction design. The presence of both bromine and chlorine atoms on the thiophene ring allows for selective functionalization, making it a highly adaptable reagent in complex synthetic pathways. When you buy 2-bromo-3-chlorothiophene, the guaranteed minimum purity of 99% ensures predictable and reliable reaction outcomes.

Synthesis Applications: A Versatile Intermediate

The value of 2-Bromo-3-chlorothiophene in organic synthesis lies in its diverse reactivity:

  • Cross-Coupling Reactions: The bromine atom, in particular, is highly amenable to palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Sonogashira couplings. These reactions are foundational for carbon-carbon bond formation, essential in building complex organic molecules.
  • Nucleophilic Substitution: The chlorine atom can also be involved in nucleophilic substitution reactions, providing another avenue for introducing various functional groups.
  • Heterocyclic Chemistry: As a thiophene derivative, it is a valuable starting material for synthesizing more complex fused heterocyclic systems, which are common motifs in pharmaceuticals and advanced materials.
  • Precursor for Specialty Chemicals: Its unique halogenation pattern makes it a sought-after intermediate for creating specialty chemicals with tailored properties for electronics, polymers, and other advanced applications.

Sourcing Strategy: Partnering with a Chinese Supplier

For researchers and procurement specialists, identifying a dependable 2-bromo-3-chlorothiophene supplier China is key to accessing this compound efficiently and affordably. At NINGBO INNO PHARMCHEM CO.,LTD., we offer competitive pricing and responsive service. We understand that procuring specialized intermediates often requires detailed technical information and reliable delivery. We encourage you to inquire about the CAS 77893-68-6 price and our capabilities for supplying consistent, high-purity material for your synthesis projects.

We are committed to facilitating scientific progress by providing essential chemical building blocks. If you are looking to buy 2-bromo-3-chlorothiophene, reach out to us for a quote and to discuss how we can support your research and development needs.