For professionals in the pharmaceutical and fine chemical industries, a deep understanding of the specifications and purity of chemical intermediates is vital for successful research, development, and manufacturing. This article focuses on 2-(1,2-Benzisoxazol-3-yl)acetic acid (CAS 4865-84-3), detailing its key characteristics and why purity is a critical factor, particularly for buyers looking to purchase this compound.

Key Specifications and Chemical Properties

2-(1,2-Benzisoxazol-3-yl)acetic acid is characterized by its chemical formula C9H7NO3 and a molecular weight of approximately 177.16 g/mol. It typically presents as a white to light yellow crystalline powder. Its chemical structure, featuring the benzisoxazole ring system fused with an acetic acid group, makes it a valuable intermediate in complex organic synthesis. While various physical properties like density and solubility can be found in technical databases, the most critical specification for its primary application—as an intermediate in Zonisamide synthesis—is its purity.

The Significance of Purity in Pharmaceutical Applications

The pharmaceutical industry operates under stringent quality regulations. For intermediates like 2-(1,2-Benzisoxazol-3-yl)acetic acid, purity directly impacts the efficacy, safety, and stability of the final Active Pharmaceutical Ingredient (API). Impurities can:

  • Alter the pharmacological profile of the drug.
  • Introduce toxicological concerns.
  • Complicate downstream purification processes.
  • Affect the shelf-life and stability of the final product.

Therefore, when procurement managers and R&D scientists seek to buy 2-(1,2-Benzisoxazol-3-yl)acetic acid, specifying a high purity level, generally 98% or higher as confirmed by techniques like Gas Chromatography (GC) or High-Performance Liquid Chromatography (HPLC), is essential. Reputable manufacturers will provide Certificates of Analysis (COA) that detail these purity levels and identify any significant impurities.

Ensuring Quality from Your Supplier

Choosing a reliable manufacturer and supplier is paramount to obtaining intermediates that meet these exacting standards. Our commitment as a producer of 2-(1,2-Benzisoxazol-3-yl)acetic acid in China is to uphold these quality benchmarks. We offer detailed specifications and comprehensive COAs with every batch. We encourage all potential buyers to inquire about our products and request samples to verify the quality and suitability for their specific needs, thereby ensuring their pharmaceutical synthesis projects are built on a foundation of high-quality materials.