For researchers and scientists engaged in early-stage R&D, understanding the fundamental properties and application potential of key chemical intermediates is crucial. Pyrimidine-5-carboxaldehyde, with CAS number 10070-92-5, is a compound that garners significant attention due to its unique structure and reactivity, making it a valuable tool in synthetic chemistry laboratories worldwide.

The chemical identity of Pyrimidine-5-carboxaldehyde lies in its molecular formula C5H4N2O and a molecular weight of 108.10 g/mol. Its structure features a pyrimidine ring, a six-membered aromatic heterocycle containing two nitrogen atoms, substituted at the 5-position with an aldehyde (-CHO) group. This aldehyde functionality is the primary reactive site, allowing for a broad spectrum of chemical modifications. Typical physical properties observed include a light yellow to yellow solid appearance and a melting point range that varies depending on purity, often cited between 38-43°C.

In research and development settings, Pyrimidine-5-carboxaldehyde is predominantly used as a building block for synthesizing more complex organic molecules. Its aldehyde group readily undergoes nucleophilic addition, oxidation, and reduction reactions. For instance, it can be reacted with organometallic reagents to form alcohols, or undergo condensation reactions with amines to produce imines, which can then be further modified. These transformations are fundamental in the discovery of new drug candidates, materials science innovations, and the development of novel agrochemicals.

Researchers looking to buy Pyrimidine-5-carboxaldehyde will often find it available from specialized chemical suppliers. The purity of the material is a critical factor, with common specifications ranging from 97% to 99% (GC or HPLC). High purity is essential to ensure that experimental results are reproducible and that side reactions are minimized, thereby saving valuable research time and resources. When sourcing, it's advisable to check the supplier's reputation and their ability to provide comprehensive technical data, including Safety Data Sheets (SDS).

The availability of Pyrimidine-5-carboxaldehyde from reliable manufacturers, often based in regions like China, makes it accessible for R&D budgets. Companies that specialize in producing such intermediates can offer competitive pricing, especially for laboratory-scale quantities. Understanding the compound's stability and recommended storage conditions (often in a cool, dark, inert atmosphere, below -20°C for long-term storage) is also vital for maintaining its integrity within the lab environment.

In summary, Pyrimidine-5-carboxaldehyde (CAS 10070-92-5) is a key intermediate for research and development, offering significant synthetic utility. Its chemical properties and reactivity make it an excellent starting material for complex molecule synthesis. By prioritizing high purity and sourcing from reputable suppliers, researchers can effectively utilize this versatile building block to advance their scientific endeavors.