The field of medicinal chemistry is continuously exploring novel molecular structures to develop more effective therapeutic agents. Quinoline derivatives, in particular, have garnered significant attention due to their diverse biological activities. Among these, quinolinecarbonitrile compounds play a crucial role as intermediates in the synthesis of various pharmaceuticals, including important oncology drugs. This article from NINGBO INNO PHARMCHEM CO.,LTD. focuses on 7-(3-Chloropropoxy)-4-hydroxy-6-methoxyquinoline-3-carbonitrile and its importance in the synthesis of Bosutinib.

7-(3-Chloropropoxy)-4-hydroxy-6-methoxyquinoline-3-carbonitrile, with its specific quinoline core and functional groups, is a highly sought-after intermediate. Its chemical structure is precisely tailored to facilitate key reactions in the production pathway of Bosutinib, a tyrosine kinase inhibitor approved for treating certain types of chronic myeloid leukemia. The presence of the chloropropoxy chain and the methoxy group on the quinoline ring system contributes to its reactivity and suitability for creating the complex molecular architecture of the final drug substance. The compound's CAS number, 214470-66-3, is a critical identifier for researchers and manufacturers in the chemical and pharmaceutical industries.

NINGBO INNO PHARMCHEM CO.,LTD., as a manufacturer and supplier of fine chemicals and pharmaceutical intermediates in China, is deeply involved in providing these advanced building blocks. We understand the intricate chemical synthesis involved in producing compounds like 7-(3-Chloropropoxy)-4-hydroxy-6-methoxyquinoline-3-carbonitrile. Our commitment extends to ensuring that our products meet the high standards required for pharmaceutical applications, enabling our clients to confidently purchase and utilize these materials in their drug development and manufacturing processes. The market for such specialized intermediates is robust, reflecting the ongoing research and development in targeted cancer therapies.

The chemical properties of 7-(3-Chloropropoxy)-4-hydroxy-6-methoxyquinoline-3-carbonitrile, such as its typical appearance as a light yellow to yellow powder and its high purity assay (≥98.0%), are essential considerations for its use. These attributes ensure predictable outcomes in synthetic reactions. For pharmaceutical companies looking to buy this intermediate, sourcing from a reliable manufacturer in China like NINGBO INNO PHARMCHEM CO.,LTD. provides access to consistent quality and competitive pricing. Our expertise in chemical synthesis and supply chain management positions us as a valuable partner for businesses seeking to advance their pharmaceutical projects.

In essence, quinolinecarbonitrile derivatives like 7-(3-Chloropropoxy)-4-hydroxy-6-methoxyquinoline-3-carbonitrile are more than just chemical compounds; they are enablers of modern medicine. By understanding their significance and ensuring reliable sourcing, the pharmaceutical industry can continue to develop and deliver life-changing treatments. NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to this vital sector by supplying high-quality intermediates. Contact us to learn more about our product offerings and how we can support your Bosutinib synthesis needs.