At NINGBO INNO PHARMCHEM CO.,LTD., we focus on providing essential components for advanced chemical processes. One such compound, (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-Methylpent-2-enoic acid (CAS 1012341-48-8), stands out for its utility in specialized synthesis. This article explores its key properties and diverse applications within the chemical sector.

This compound is characterized by its molecular formula C23H27NO4 and a molecular weight of 381.46. It typically presents as a white to off-white solid, with a melting point in the range of 188-191°C. The presence of a biphenyl group, a protected amino acid moiety, and a reactive carboxylic acid group makes it a versatile molecule for organic chemists. The tert-butoxycarbonyl (Boc) group offers protection to the amine during synthetic transformations, a common strategy in peptide and complex molecule synthesis. This characteristic also positions it as a valuable protected amino acid derivative.

The primary application driving the demand for this compound is its role as a crucial intermediate in the pharmaceutical industry, particularly for the production of sacubitril. The synthesis of sacubitril involves multiple complex steps, and this specific intermediate provides a pre-assembled chiral center and a protected amine, significantly streamlining the process. Therefore, its use in sacubitril intermediate production is well-established.

Beyond its pharmaceutical relevance, the compound is also a valuable asset in the broader field of fine chemical production. Its unique structure, featuring the biphenyl system, makes it an attractive building block for researchers developing novel materials, specialized reagents, or advanced organic compounds. Chemists seeking a specific biphenyl derivative chemical for their research will find this molecule to be of significant interest due to its functional group versatility and defined stereochemistry.

Ensuring the quality and purity of such specialized chemicals is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering intermediates that meet rigorous standards, enabling reliable and efficient organic synthesis. Whether you are involved in early-stage drug discovery, process development, or large-scale manufacturing, having access to precise and pure building blocks like (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-Methylpent-2-enoic acid is essential for success. We pride ourselves on supporting chemical innovation by providing the foundational materials necessary for groundbreaking research and development.