In the pharmaceutical industry, the development of targeted therapies relies heavily on specialized chemical compounds. Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)- (CAS 162401-32-3), commonly known as Roflumilast, stands out as a critical intermediate with significant therapeutic applications, primarily in managing respiratory diseases such as Chronic Obstructive Pulmonary Disease (COPD). Understanding its role and how to effectively source it is vital for R&D scientists and procurement managers.

Roflumilast functions as a selective, long-acting phosphodiesterase-4 (PDE4) inhibitor. This mechanism allows it to reduce inflammation in the airways, thereby alleviating symptoms and preventing exacerbations in patients with severe COPD. Its development and production are complex, making the availability of high-quality intermediates like CAS 162401-32-3 a key factor. For businesses looking to buy Roflumilast intermediate China, identifying a reputable supplier is the first step towards a successful partnership.

Pharmaceutical Applications and Sourcing Strategies:

  • Therapeutic Significance: Roflumilast's primary application is in the treatment of severe COPD, offering a new avenue for managing this debilitating condition. Its unique mechanism targets inflammation pathways, distinguishing it from traditional bronchodilators. This therapeutic importance drives the demand for its intermediates.
  • Role as an Intermediate: CAS 162401-32-3 is a crucial building block in the multi-step synthesis of Roflumilast. The precise chemical structure and high purity of this benzamide derivative are essential for ensuring the efficacy and safety of the final drug product.
  • Sourcing from China: China has become a global leader in the manufacturing of pharmaceutical intermediates due to its advanced chemical infrastructure and competitive pricing. When sourcing this compound, it is advisable to partner with established manufacturers who can guarantee consistent quality and compliance with international standards. We are a prominent supplier committed to this.
  • Quality Assurance: For pharmaceutical applications, the purity of the intermediate is paramount. We ensure our products meet rigorous quality specifications. When you purchase CAS 162401-32-3 from us, you can expect detailed Certificates of Analysis (CoA) and adherence to pharmaceutical-grade requirements.
  • Bulk Procurement Advantages: For companies planning commercial-scale production, securing a bulk supply of Roflumilast intermediates is essential. We offer competitive price points and reliable delivery for large orders, supporting your production timeline and cost-efficiency goals.

By focusing on reliable sourcing and stringent quality control, pharmaceutical companies can ensure the efficient development and manufacturing of Roflumilast. If you are in need of this vital chemical intermediate, our team is ready to assist you with your requirements, offering expertise and dependable supply from our manufacturing base.