The indole scaffold is a prevalent structural motif in many biologically active compounds and pharmaceuticals. Consequently, indole derivatives are highly sought after as intermediates in drug synthesis. This article focuses on a specific, important example: 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile (CAS 276863-95-7), a critical intermediate in the production of Vilazodone. Understanding its role and how to effectively source it is vital for pharmaceutical research and development professionals.

3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile is characterized by its indole core, functionalized with both a nitrile group at the 5-position and a 4-chlorobutanoyl chain at the 3-position. This unique structure makes it an ideal building block for complex API synthesis. The primary application for this compound is in the manufacturing of Vilazodone, an antidepressant medication. The requirement for high purity, typically above 99%, and its appearance as a white crystalline powder are key specifications that buyers should always verify when they look to buy 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile.

For effective procurement, identifying a reliable manufacturer and supplier is paramount. Global sourcing often leads to China, which boasts extensive capabilities in fine chemical synthesis and intermediate production. A reputable Chinese manufacturer can offer competitive pricing and large-scale production capacity, essential for supporting both research quantities and bulk commercial orders. When evaluating suppliers, pay close attention to their quality assurance protocols, their ability to provide comprehensive technical documentation, and their responsiveness to inquiries.

The price of CAS 276863-95-7 can be influenced by market demand, purity levels, and order volume. It is advisable for procurement managers to obtain quotes from several qualified suppliers to ensure they are securing the best possible value. However, the decision should not be solely based on the lowest price. Factors such as supply chain stability, the supplier's reputation for quality, and their adherence to regulatory standards are equally important for long-term project success.

As a dedicated supplier of pharmaceutical intermediates, we offer high-quality 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile, ensuring that your synthesis projects benefit from reliable materials. Our commitment as a Chinese manufacturer means we are well-positioned to meet your diverse needs, from laboratory-scale research to large commercial batches. We invite you to contact us to learn more about our product specifications, obtain a quote, and discuss how we can be your trusted partner for this and other essential indole-based intermediates.