For any chemist or procurement manager in the pharmaceutical or fine chemical industries, understanding the precise specifications of a chemical intermediate is paramount. These details dictate the compound's suitability for specific applications, its handling requirements, and the reliability of its performance in synthesis. 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (CAS: 954112-61-9) is a prime example where granular knowledge of its properties is essential.

The primary specification that buyers scrutinize is purity. For 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde, manufacturers typically offer high levels of purity, often stated as 99% min. This high purity is not merely a number; it signifies that the batch contains minimal impurities, which is critical for pharmaceutical applications where even trace contaminants can affect the efficacy, safety, and regulatory compliance of the final drug product. Impurities can interfere with desired reactions, lead to unwanted side products, or possess their own toxicological profiles.

Another key physical property is the melting point. The reported range for 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde is typically between 199-202 °C. This relatively high melting point indicates that the compound is a stable solid under standard laboratory conditions. A sharp melting point range generally suggests a pure substance, while a broad or depressed range might hint at the presence of impurities. This information is vital for storage, handling, and designing reaction conditions, especially when considering solubility and thermal stability.

The molecular formula, C8H5ClN2O, and the corresponding molecular weight of 180.59 g/mol are fundamental identifiers. These values are crucial for stoichiometric calculations in synthesis. Knowing the exact mass ensures that chemists can accurately weigh out the required amounts for reactions, which is fundamental for reproducible results and efficient use of precious materials. The inclusion of density (predicted at 1.521±0.06 g/cm3) further aids in understanding its physical characteristics, though it is less critical for immediate synthetic planning than purity or melting point.

When looking to buy this compound, especially from manufacturers based in China, it is vital to request a Certificate of Analysis (CoA). This document will officially state the purity, melting point, and other key specifications for the specific batch being purchased. It serves as a guarantee of quality and a record of compliance. Reputable suppliers will readily provide COAs and often offer free samples for verification purposes. Understanding these specifications empowers researchers to make informed decisions, ensuring they procure the right intermediate for their critical synthesis projects.

In essence, the specifications of 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde are more than just data points; they are the quality markers that define its utility and value in the chemical industry. By paying close attention to these details, researchers can confidently engage with manufacturers and suppliers to secure the high-quality intermediates necessary for groundbreaking discoveries.