For professionals in the chemical and pharmaceutical sectors, a deep understanding of specific compounds is essential for successful research, development, and manufacturing. (S)-(-)-1,2,3,4-Tetrahydro-naphthoic Acid, identified by CAS number 85977-52-2, is a prime example of a highly valuable fine chemical intermediate. Its unique chiral structure and versatile applications, particularly in pharmaceutical synthesis, make it a compound of significant interest. This article aims to provide a comprehensive overview of its specifications and uses, emphasizing the advantages of sourcing from a reliable manufacturer in China.

Chemical Identity and Key Specifications

(S)-(-)-1,2,3,4-Tetrahydro-naphthoic Acid has the molecular formula C11H12O2 and a molecular weight of approximately 176.21 g/mol. A critical characteristic of this compound is its appearance: typically a white to off-white powder. This physical form is conducive to various handling and processing methods in laboratory and industrial settings. The melting point, commonly reported in the range of 54-56°C, is a key indicator of its purity and stability. When you look to buy this chemical, it’s crucial to verify its purity, which is often specified as ≥98%. This high level of purity ensures that it is suitable for sensitive applications like pharmaceutical synthesis, where even minor impurities can have significant consequences. The chemical is also known by synonyms such as (1S)-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid and Palonosetron Intermediate 1, reflecting its specific applications and stereochemistry.

Primary Applications in Pharmaceutical and Chemical Industries

The primary driver for the demand of (S)-(-)-1,2,3,4-Tetrahydro-naphthoic Acid is its indispensable role in the synthesis of active pharmaceutical ingredients (APIs). Its most well-known application is as a key intermediate in the production of Palonosetron hydrochloride, a vital antiemetic drug that significantly improves patient comfort during cancer treatment. The chiral nature of the molecule is critical for its pharmacological activity, making this specific enantiomer essential. Furthermore, the compound serves as a versatile building block in general organic synthesis, allowing chemists to construct complex molecular architectures. It is also recognized for its use in preparing Dipeptidyl Boronate Proteasome Inhibitors, contributing to the development of new therapeutic agents targeting diseases like cancer.

Sourcing Strategy: The China Advantage

For companies worldwide seeking to procure (S)-(-)-1,2,3,4-Tetrahydro-naphthoic Acid, partnering with Chinese manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. offers distinct advantages. China's robust chemical industry provides access to advanced manufacturing processes, economies of scale, and competitive pricing. By choosing a dedicated supplier in China, businesses can ensure a reliable and consistent supply of this high-purity intermediate. Our commitment to quality assurance, adherence to international standards, and efficient logistics make us a preferred partner for pharmaceutical companies and chemical distributors. When you need to buy this intermediate, consider the benefits of a direct relationship with a trusted manufacturer for consistent quality and optimal cost-effectiveness.

Handling and Storage Recommendations

To maintain the integrity and purity of (S)-(-)-1,2,3,4-Tetrahydro-naphthoic Acid, proper storage and handling are crucial. It should be stored in a cool, dry, and well-ventilated place, away from direct sunlight and heat sources. Keeping the container tightly closed is important to prevent moisture absorption. Adhering to these guidelines ensures the compound remains stable and ready for use in demanding synthetic applications, safeguarding your investment and project timelines.

In summary, (S)-(-)-1,2,3,4-Tetrahydro-naphthoic Acid is a high-value chemical intermediate with critical applications in the pharmaceutical industry. Understanding its specifications, applications, and the benefits of sourcing from reputable manufacturers in China is essential for procurement and R&D professionals.