In the realm of organic chemistry, certain compounds serve as foundational pillars for a vast array of industrial applications. (2-Bromoethyl)benzene, identified by CAS number 103-63-9, is one such critical intermediate. Its unique structure and reactive properties make it indispensable in sectors ranging from pharmaceuticals to agrochemicals and beyond. As a leading manufacturer and supplier, we aim to demystify this compound and highlight its significance for B2B professionals.

Synthesis Pathways for (2-Bromoethyl)benzene

The production of (2-Bromoethyl)benzene can be achieved through several synthetic routes, each with its advantages. A common and efficient laboratory method involves the anti-Markovnikov addition of hydrogen bromide (HBr) gas to styrene, typically in the presence of an initiator such as azobisisobutyronitrile (AIBN). This reaction, often carried out in a suitable solvent like n-heptane, yields β-bromophenylethane with high selectivity and purity, often exceeding 95% yield and 99% purity. This method is favored for its use of readily available and cost-effective starting materials, making it suitable for large-scale manufacturing.

Another established industrial method involves the reaction of 2-phenylethanol with hydrogen bromide or hydrobromic acid. While effective, traditional processes may face challenges related to raw material costs, utilization rates, and product separation complexity. Continuous research and process optimization by manufacturers aim to enhance efficiency and sustainability in production.

Key Applications Driving Demand

(2-Bromoethyl)benzene's versatility is evident in its broad application spectrum:

  • Pharmaceutical Intermediates: It serves as a crucial building block in the synthesis of various Active Pharmaceutical Ingredients (APIs). Its structure is instrumental in creating complex molecules essential for drug development, including antibacterial agents and compounds used in neurological treatments. Researchers seeking to buy high-purity intermediates for drug synthesis will find its properties particularly valuable.
  • Agrochemical Intermediates: The compound is vital for the production of pesticides, herbicides, and other crop protection agents. Its incorporation into these molecules helps create effective solutions for modern agriculture, contributing to food security.
  • Organic Synthesis Reagent: As a reactive aryl bromide, it's a staple in general organic synthesis laboratories. It participates in numerous reactions, enabling chemists to construct novel organic molecules and materials for diverse research purposes.
  • Specialty Chemicals: Beyond these major sectors, (2-Bromoethyl)benzene is used in the synthesis of various specialty chemicals, contributing to advancements in materials science and other high-tech fields.

Choosing a Reliable Supplier

For businesses requiring (2-Bromoethyl)benzene, partnering with a reputable manufacturer is essential. We pride ourselves on offering high-purity (99.5%) material with a stable supply chain, directly from our factory in China. Our commitment to quality assurance ensures that you receive a consistent product suitable for your critical applications. When you need to purchase this key intermediate, consider our capabilities for competitive pricing and reliable delivery. We invite you to send an inquiry to discuss your specific needs and explore how we can support your manufacturing and research endeavors.