2-Fluoro-4-iodoaniline (CAS 29632-74-4) is a halogenated aromatic amine that has garnered significant attention in the chemical industry due to its versatile reactivity and broad range of applications. As a crucial intermediate in organic synthesis, it serves as a foundational molecule for creating complex pharmaceuticals, agrochemicals, and advanced materials. Understanding its properties and synthetic utility is essential for chemists and procurement specialists seeking to leverage its potential.

The chemical structure of 2-Fluoro-4-iodoaniline, featuring both a fluorine and an iodine atom on an aniline ring, provides distinct advantages in synthetic chemistry. The fluorine atom often enhances metabolic stability and lipophilicity in derived compounds, particularly relevant in pharmaceutical design. Simultaneously, the iodine atom is an excellent leaving group and is highly amenable to a variety of metal-catalyzed cross-coupling reactions, such as Suzuki, Heck, Stille, and Sonogashira couplings. This dual functionality allows for regioselective modifications and the construction of diverse molecular scaffolds. When researchers need to buy such a precisely functionalized molecule, its availability from a reputable supplier is key.

The synthesis of 2-Fluoro-4-iodoaniline typically involves multi-step processes starting from simpler fluorinated or iodinated aromatic precursors. These routes are optimized by manufacturers to achieve high yields and purity, often exceeding 98.0%. For instance, it can be prepared through selective halogenation and reduction sequences. The physical properties, such as its appearance as a light yellow to brown crystalline powder and a melting point of 55-57 °C, are important indicators of its quality and handling characteristics. Understanding these parameters helps in its effective integration into various synthetic workflows.

The applications of 2-Fluoro-4-iodoaniline are far-reaching. In the pharmaceutical sector, it acts as a vital building block for synthesizing active pharmaceutical ingredients (APIs), particularly in areas like oncology and antiviral research. Its incorporation can lead to drug candidates with improved efficacy and pharmacokinetic profiles. Beyond pharmaceuticals, it plays a role in the development of novel dyes, pigments, and functional materials for electronic applications. For companies looking to purchase this intermediate, partnering with a knowledgeable manufacturer in China ensures not only competitive pricing but also access to technical expertise and reliable supply. We are committed to being that source for your advanced chemical needs.

To effectively utilize 2-Fluoro-4-iodoaniline, chemists and formulators rely on its consistent availability and well-defined specifications. We are dedicated to providing high-quality intermediates that empower innovation across industries. Explore our product offerings and request a quote to secure your supply.