For professionals in chemical synthesis and material science, understanding the synthesis and versatile applications of key intermediates is crucial for innovation. 4-Maleimidobutyric Acid (CAS: 57078-98-5) is one such compound, widely recognized for its utility in bioconjugation, pharmaceutical research, and polymer chemistry. Its unique structure, featuring both a maleimide and a carboxylic acid group, allows for a broad spectrum of chemical transformations.

The synthesis of 4-Maleimidobutyric Acid typically involves reactions that functionalize a four-carbon chain with both a maleimide ring and a carboxylic acid. While specific proprietary synthesis routes vary among manufacturers, the general principle often involves cyclization reactions to form the maleimide ring and subsequent attachment or modification to introduce the terminal carboxyl group. Ensuring high purity, often above 97% via HPLC, is a critical aspect of its manufacturing process for its intended applications.

The applications of this compound are diverse and impactful. In bioconjugation, its maleimide group readily reacts with thiols, enabling the precise labeling of proteins, antibodies, and peptides. This is fundamental in developing diagnostic assays, targeted drug delivery systems, and biopharmaceuticals. For researchers in this field, identifying a dependable supplier who can provide consistent quality is essential for reproducible experimental outcomes.

Beyond biological applications, 4-Maleimidobutyric Acid serves as a valuable monomer or crosslinking agent in polymer chemistry. It can be used to synthesize functional polymers or modify existing ones, imparting specific properties such as improved surface adhesion or responsiveness. For industry professionals looking to buy this chemical, understanding these applications helps in specifying requirements and ensuring the material meets project goals.

We, as a dedicated manufacturer and supplier, are committed to providing high-quality 4-Maleimidobutyric Acid. Our focus on stringent quality control ensures that our product is suitable for even the most demanding applications. We encourage you to reach out to us for more information, to request a quote, or to discuss bulk purchasing options for your synthesis needs. Partner with us for your supply of this essential chemical intermediate.