The chemical synthesis of complex molecules is the bedrock of pharmaceutical innovation and advanced materials development. Among the vast array of chemical intermediates, chiral compounds like (R)-2-Piperazinecarboxylic Acid Dihydrochloride (CAS 126330-90-3) play an increasingly vital role. As a manufacturer focused on high-quality intermediates, we aim to provide a clear understanding of this compound’s importance, its synthesis, and its diverse applications.

(R)-2-Piperazinecarboxylic Acid Dihydrochloride is a derivative of piperazine, a heterocyclic amine. The molecule possesses a chiral center at the 2-position of the piperazine ring, making the (R)-enantiomer distinct and highly valuable for stereoselective synthesis. The dihydrochloride salt form enhances its stability and ease of handling, typical for amine-containing compounds in laboratory and industrial settings.

Synthesis Pathways and Manufacturing Excellence

The synthesis of enantiomerically pure compounds like (R)-2-Piperazinecarboxylic Acid Dihydrochloride typically involves either the resolution of a racemic mixture or an asymmetric synthesis approach. Manufacturers often employ specialized chiral auxiliaries or catalysts to direct the formation of the desired (R)-enantiomer. Achieving high enantiomeric excess (ee) and chemical purity is a hallmark of a skilled chemical manufacturer. Our production processes are designed to optimize yield and purity, ensuring that when you buy this product, you receive a material that meets exacting scientific standards. We leverage established synthetic methodologies and continuous process improvements to maintain consistent quality.

Key Applications in Research and Development

The demand for (R)-2-Piperazinecarboxylic Acid Dihydrochloride stems from its significant utility in several critical areas:

  1. Pharmaceutical Synthesis: It serves as a fundamental building block for the synthesis of various Active Pharmaceutical Ingredients (APIs). Notably, it is a precursor for generating (R)-enantiomers of anthramycin analogs, which are investigated for their potent antiproliferative properties, making them candidates for cancer therapies.
  2. Chiral Ligand Preparation: This compound is essential for preparing chiral ligands used in asymmetric catalysis. These ligands, when complexed with metals, create catalysts that selectively produce one enantiomer of a target molecule. This is crucial for producing enantiomerically pure drugs, thereby enhancing their therapeutic efficacy and safety profile.
  3. General Organic Synthesis: Its unique structure, featuring both a carboxylic acid and a secondary amine within a chiral framework, makes it a versatile intermediate for a wide range of complex organic syntheses.

Partnering for Success

For companies seeking to buy (R)-2-Piperazinecarboxylic Acid Dihydrochloride, choosing a manufacturer with a strong commitment to quality, scientific expertise, and reliable supply is paramount. At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on our ability to deliver these qualities. We understand that our clients rely on us for critical intermediates that drive their innovation. By focusing on rigorous quality control and efficient manufacturing, we ensure that our products, including (R)-2-Piperazinecarboxylic Acid Dihydrochloride, meet the demanding requirements of the pharmaceutical and fine chemical industries.

We invite researchers and procurement specialists to explore the potential of (R)-2-Piperazinecarboxylic Acid Dihydrochloride and to consider us as your trusted supplier. Your success in synthesis and development is our ultimate goal.