N-Acetylcysteamine (CAS 1190-73-4) is a compound that holds significant interest in the fields of organic chemistry and pharmaceutical manufacturing. Its utility as a chemical intermediate stems from its molecular structure and reactive functional groups. For researchers and procurement specialists, understanding its synthesis, properties, and market dynamics is crucial for successful sourcing and application. This article provides an overview of N-Acetylcysteamine, including its synthesis, key properties, and market considerations, with an emphasis on sourcing from reliable manufacturers.

Chemical Profile and Synthesis
N-Acetylcysteamine, also known as N-(2-Mercaptoethyl)acetamide, has the molecular formula C4H9NOS and a molecular weight of approximately 119.19 g/mol. It typically presents as a clear liquid with a characteristic odor, owing to the presence of the thiol group. Its melting point is around 6-7°C, and its boiling point is approximately 138-140°C at 7 mmHg. These physical properties are important for handling and storage.

The synthesis of N-Acetylcysteamine commonly involves the acetylation of cysteamine (2-aminoethanethiol). This reaction typically uses acetic anhydride or acetyl chloride as the acetylating agent in a suitable solvent, often under controlled temperature conditions. The process yields N-Acetylcysteamine with a protected thiol group, which can then be utilized in further chemical transformations. Manufacturers focus on optimizing this process to achieve high yields and the required purity levels (commonly 94% or 97%+).

Applications in Industry
The primary application of N-Acetylcysteamine is as an intermediate in the synthesis of a wide array of compounds, particularly in the pharmaceutical sector. It serves as a precursor for APIs and other complex organic molecules, including natural product analogs and novel therapeutic agents. Its reactive thiol group allows for diverse reactions, such as nucleophilic substitutions and disulfide bond formations, making it a valuable tool for synthetic chemists.

Market Trends and Sourcing Considerations
The market for N-Acetylcysteamine is closely tied to the growth of the pharmaceutical and fine chemical industries. Demand is driven by ongoing research and development into new drugs and advanced materials. Sourcing N-Acetylcysteamine, especially in bulk quantities, often leads buyers to consider manufacturers in regions with strong chemical production capabilities, such as China.

When looking to buy N-Acetylcysteamine, it is imperative to partner with a reputable manufacturer or supplier. Key considerations include:

  • Purity: Ensure the specified purity meets your application's requirements.
  • Reliability: A consistent supply chain and dependable manufacturer are essential.
  • Pricing: Obtain competitive quotes for your required quantities.
  • Documentation: Always request CoA and SDS for quality assurance and safety compliance.

As a dedicated N-Acetylcysteamine manufacturer, we are committed to providing high-quality products at competitive prices. We understand the importance of this intermediate for your synthesis needs and offer comprehensive support. Contact us to learn more about our product specifications, pricing, and how to place an order for N-Acetylcysteamine (CAS 1190-73-4).