The journey of a pharmaceutical drug from concept to patient involves meticulous chemical synthesis and a robust supply chain. Central to this process are pharmaceutical intermediates, the building blocks that form the backbone of active pharmaceutical ingredients (APIs). 11-Alpha-Hydroxycanrenone Methyl Ester, identified by CAS number 192704-56-6, is a prime example of such a critical intermediate, primarily used in the synthesis of Eplerenone. This article aims to shed light on its synthesis, properties, and the benefits of sourcing it from reliable manufacturers.

The synthesis of 11-Alpha-Hydroxycanrenone Methyl Ester itself is a multi-step process, often derived from related steroid precursors. While the detailed proprietary synthesis routes vary among manufacturers, the goal is consistent: to produce a compound of high purity with the correct stereochemistry. Information from chemical databases suggests that methods involve functional group transformations and cyclization reactions. The resulting compound is typically a white to off-white solid, a characteristic that is important for its handling and subsequent reaction steps. Its molecular formula is C24H32O6, with a molecular weight of approximately 416.51 g/mol.

For pharmaceutical companies, the reliability of the supply of this intermediate is paramount. Eplerenone is a crucial drug for managing hypertension and heart failure, and any disruption in the supply of its precursor can have significant consequences. This is where experienced China manufacturers play a pivotal role. They have the capacity, expertise, and quality control systems to produce 11-Alpha-Hydroxycanrenone Methyl Ester consistently and in large volumes. When you intend to purchase this CAS number, engaging with a reputable supplier ensures that you receive not only the product but also the supporting documentation and a stable supply commitment.

The sourcing process for pharmaceutical intermediates often involves rigorous supplier qualification. Potential buyers look for manufacturers who can demonstrate adherence to Good Manufacturing Practices (GMP), though not always mandatory for intermediates, and provide detailed analytical data. Information regarding solubility (e.g., slightly soluble in chloroform, DMSO, and methanol), stability (hygroscopic), and precise assay values are vital for process chemists and formulation scientists. Working with a manufacturer that provides this level of detail fosters confidence and streamlines development.

Furthermore, the competitive landscape in chemical manufacturing in China means that buyers can often find attractive pricing for 11-Alpha-Hydroxycanrenone Methyl Ester, especially when purchasing in bulk. However, price should not be the sole determinant. The long-term viability of a supplier, their commitment to quality, and their ability to innovate and adapt to evolving regulatory requirements are equally important. As a proactive manufacturer, we are dedicated to providing both exceptional product quality and a seamless procurement experience for our global clientele, ensuring your Eplerenone production runs smoothly.

In conclusion, understanding the synthesis and ensuring a stable supply of 11-Alpha-Hydroxycanrenone Methyl Ester (CAS 192704-56-6) is critical for pharmaceutical manufacturers. By partnering with trusted China suppliers, companies can secure a high-quality, cost-effective source for this essential Eplerenone intermediate, thereby contributing to the availability of vital cardiovascular medications.