5-Bromo-2-methoxyphenol, identified by its CAS number 37942-01-1, is a significant fine chemical intermediate with a well-defined set of chemical properties that dictate its utility in various scientific and industrial applications. Understanding these properties is crucial for researchers, chemists, and procurement professionals seeking to leverage this compound effectively. This article delves into its characteristics and common applications, offering insights from a leading chemical supplier perspective.

Chemically, 5-Bromo-2-methoxyphenol, also known by synonyms such as 3-Hydroxy-4-methoxybromobenzene or 5-Bromoguaiacol, is an aromatic organic compound. Its molecular formula is C7H7BrO2, with a molecular weight of approximately 203.03 g/mol. Physically, it typically appears as a white crystalline powder. This solid form, combined with its characteristic melting point of 64-70°C, makes it relatively easy to handle and store under appropriate conditions, such as a cool environment. Its boiling point is approximately 150°C at 20mmHg, indicating its stability under moderate vacuum distillation.

The functional groups present—a bromine atom, a methoxy group (-OCH3), and a hydroxyl group (-OH)—render 5-Bromo-2-methoxyphenol highly reactive and versatile. The bromine atom is a good leaving group and is susceptible to nucleophilic substitution reactions or can participate in palladium-catalyzed cross-coupling reactions, which are fundamental in organic synthesis. The phenolic hydroxyl group can undergo O-alkylation, esterification, or serve as a directing group in electrophilic aromatic substitution. The methoxy group influences the electronic distribution within the aromatic ring, affecting its reactivity.

The primary application area for 5-Bromo-2-methoxyphenol lies in its role as a building block or intermediate in the synthesis of more complex organic molecules. This includes its use in the pharmaceutical industry, where it can be a precursor to Active Pharmaceutical Ingredients (APIs). It is also valuable in the agrochemical sector and in the development of specialty chemicals and materials science research. For example, researchers looking to buy this compound often intend to use it in custom synthesis projects or as a starting material for novel compound libraries.

When sourcing 5-Bromo-2-methoxyphenol, it is imperative to secure high-quality material. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensure that the product meets stringent purity standards, typically ≥98.0%. This high purity is essential to prevent unwanted side reactions and ensure the successful outcome of complex synthetic procedures. The company's ability to supply this intermediate in various quantities, from grams for R&D to larger quantities for pilot-scale production, makes it a valuable partner for a wide range of clients.

In essence, the chemical properties of 5-Bromo-2-methoxyphenol—its physical state, reactivity, and structural features—make it a cornerstone compound for organic chemists. Its widespread application as an intermediate underscores the importance of reliable suppliers who can consistently deliver high-purity products. For those seeking to purchase this compound, engaging with experienced manufacturers offers not only competitive pricing but also the assurance of quality and supply chain stability.