For scientists and engineers working with organic compounds, a thorough understanding of chemical properties is fundamental to successful synthesis and application. 2,6-Difluorobenzylamine, identified by its CAS number 69385-30-4, is a molecule whose specific characteristics make it a valuable intermediate in various chemical processes, particularly within the pharmaceutical and fine chemical industries.

At its core, 2,6-Difluorobenzylamine is a primary amine derivative of toluene, with two fluorine atoms strategically placed on the benzene ring at the ortho positions relative to the methylamine group. This structural arrangement significantly influences its reactivity and physical attributes. Manufacturers typically specify its appearance as a clear, colorless to yellow liquid, indicating its phase at standard conditions. The purity, often stated as 97%, is a critical parameter for chemists looking to buy this compound, ensuring reliable outcomes in complex reactions.

Key physical properties provided by suppliers like NINGBO INNO PHARMCHEM CO., LTD. include a boiling point of 174-177°C and a density of 1.197 g/mL at 25°C. The flash point of 150°F is also an important safety consideration for handling and storage. These details are vital for chemists designing reaction protocols, scale-up processes, and ensuring safe laboratory or industrial environments. Understanding these parameters helps procurement managers select appropriate handling equipment and storage conditions.

The presence of fluorine atoms on the aromatic ring impacts the electron distribution, making the benzyl carbon slightly more electrophilic and potentially influencing the basicity of the amine group. This electronic effect can be leveraged in various synthesis strategies, such as nucleophilic substitutions or condensation reactions. Researchers often explore how these fluorinated motifs contribute to the overall stability, lipophilicity, and biological activity of the target molecules they are synthesizing.

The compound's role as an intermediate means it is frequently subjected to further chemical transformations. For instance, it can react with isocyanates to form urea derivatives, or with aldehydes and ketones to form imines, which can then be reduced to secondary amines. The guanidine hydrochloride and formamidine derivatives mentioned in its application profile highlight its utility in creating compounds with specific biological activities, common in pharmaceutical research.

For chemists and procurement professionals, appreciating these chemical properties is key to unlocking the full potential of 2,6-Difluorobenzylamine. When searching for this compound, understanding the specifications provided by manufacturers and suppliers, like their commitment to quality and proper storage recommendations (e.g., storing in a dark place under inert atmosphere), ensures that the material will perform as expected. This informed approach guarantees that the purchase of 2,6-Difluorobenzylamine contributes positively to the efficiency and success of chemical synthesis endeavors.