For professionals in the chemical and pharmaceutical sectors, a deep understanding of a compound's properties is fundamental to its effective application. 2-Chloro-3-(trifluoromethyl)pyridine, identified by CAS number 65753-47-1, is a specialized fluorinated pyridine derivative that has garnered attention for its utility as a vital building block in complex organic synthesis. Its unique chemical and physical characteristics make it an indispensable component in the development of advanced pharmaceuticals, particularly in the realm of pain management.

One of the most notable aspects of 2-Chloro-3-(trifluoromethyl)pyridine is its structure, featuring both a chlorine atom and a trifluoromethyl group on a pyridine ring. This specific arrangement imparts reactivity and stability, making it an excellent precursor for targeted molecular design. As a manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. ensures that this compound is supplied with a high purity level, typically ≥98.0%, which is crucial for downstream applications where precision is paramount. The compound typically presents as a colorless crystalline powder, indicating a solid state at room temperature.

The reported physical properties, such as its melting point ranging from 36-40°C and a boiling point around 181.7°C at atmospheric pressure, provide essential data for chemists designing synthetic processes. Its density of approximately 1.4 g/cm³ also contributes to understanding its physical behavior. These attributes, combined with its solubility characteristics, allow for its effective use in various reaction conditions. When considering a supplier, it's important to ensure they can provide accurate specifications and reliable product quality.

The primary application of 2-Chloro-3-(trifluoromethyl)pyridine is in the synthesis of high-affinity TRPV1 (vanilloid receptor 1) antagonists. These compounds are being explored extensively for their potential as novel analgesics, targeting pain and inflammatory pathways. For researchers and formulators looking to buy this intermediate, understanding its role in pharmaceutical development is key. Availability from a trusted supplier in China often ensures competitive price and accessible quantities, from research-scale milligrams to industrial tons.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality chemical intermediates like 2-Chloro-3-(trifluoromethyl)pyridine. We invite you to contact us to request a quote and to learn more about how our products can support your innovative pharmaceutical research and development projects. Partner with us for reliable sourcing and exceptional chemical expertise.