For professionals in chemical research and development, a thorough understanding of a compound's chemical and physical properties is fundamental to its effective utilization. 4-Chloromethyl-5-methyl-1,3-dioxol-2-one, identified by CAS number 80841-78-7, is a prime example of a fine chemical intermediate whose properties dictate its role in sophisticated synthesis pathways. Sourcing this compound from reliable manufacturers ensures access to materials that meet specific analytical standards.

At its core, 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is a dioxolone derivative with the molecular formula C5H5ClO3. Its molecular weight is approximately 148.54 g/mol. The compound is characterized by a light yellow to brown liquid appearance, a density of 1.362 g/cm³, and a boiling point of 163.228 °C at standard atmospheric pressure (760 mmHg). Its flash point is 66.729 °C, indicating moderate flammability, which is a standard consideration in handling chemical reagents.

The reactivity of 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is largely attributed to its chloromethyl group. This functional group makes the molecule susceptible to nucleophilic substitution reactions, allowing it to readily react with various nucleophiles. This characteristic is precisely what makes it an invaluable intermediate in organic synthesis, enabling the formation of new carbon-carbon or carbon-heteroatom bonds. For example, in the synthesis of Olmesartan Medoxomil, this reactive site is crucial for forming key linkages within the drug molecule's structure.

While the compound exhibits slight solubility in chloroform and methanol, its solubility in water is limited, typical for many organic intermediates. The topological polar surface area (TPSA) of 35.5 Ų and a LogP value of 1.1 provide insights into its behavior in different solvent systems and its potential for membrane permeability, which can be relevant in pharmaceutical applications.

For procurement managers and researchers, understanding these properties is essential for selecting appropriate reaction conditions, storage requirements, and safety protocols. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. provide detailed specifications and technical data, ensuring that clients receive materials that precisely match their analytical needs. When you buy this intermediate, you are investing in a well-characterized chemical entity, backed by the expertise of a leading Chinese supplier, ready to support your most demanding synthetic projects.